Evidence map›Paper›PMID 33541972›Full record

ArticleBMJ case reports2021

False elevations in urinary metanephrines: under-recognised pitfall with 24-hour urinary volume collection.

Terry Shin, Thanh Duc Hoang, Mary Thomas Plunkett, Mohamed K M Shakir

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Terry ShinEndocrinology, Womack Army Medical Center, Fort Bragg, North Carolina, USA terrytshin@gmail.com.
Thanh Duc HoangUniformed Services University of the Health Sciences, Bethesda, MD, USA.
Mary Thomas PlunkettEndocrinology, Womack Army Medical Center, Fort Bragg, North Carolina, USA.
Mohamed K M ShakirUniformed Services University of the Health Sciences, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One pitfall in 24-hour urine collection is the input of incorrect urinary volume by the reference laboratory. This may lead to an incorrect diagnosis of pheochromocytoma or paraganglioma. A 48-year-old African-American woman was seen in the clinic for an elevated 24-hour urine metanephrine screen during workup for secondary hypertension. Urine volume was found to be incorrectly inputted by the lab as 9750 mL rather than 975 mL. The urinary metanephrines were then recalculated and the 24-hour urinary metanephrines resulted within normal limits. This case highlights this unique and potentially under-recognised error in testing with 24-hour urine volume collection.

Indexed as

MetanephrineUrinalysisAdrenal Gland NeoplasmsBlack or African AmericanBlack PeopleFemaleHumansHypertensionMiddle AgedParagangliomaPheochromocytomaMetanephrineadrenal disordersendocrinology

Identifiers

PMID33541972
PMCPMC7868217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.