Evidence map›Paper›PMID 33541956›Full record

ArticleBMJ case reports2021

Case of recurrent cerebral haemorrhage in an older adult man who uses dimethylsulfoxide (DMSO) for self-management of low mood and pain.

Jonathan Olds, Mohamed Yousif, Oladotun Abidakun, Abigail Cannon

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathan OldsLater Life Liaison Psychiatry, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK jonathan.olds@nhs.net.
Mohamed YousifDepartment of Medicine, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Oladotun AbidakunDepartment of Stroke Medicine, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Abigail CannonDepartment of Geriatric Medicine, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
University Hospitals Bristol and Weston NHS Foundation TrustUniversity Hospitals Bristol NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a man in his 70s who had suffered two separate frontal lobe haemorrhages in the context of using dimethylsulfoxide (DMSO) to manage his low mood. The known pathophysiology of DMSO renders it a likely causative agent of the recurrent intracerebral haemorrhages. This case highlights the need for clinicians to robustly enquire about a patient's use of over-the-counter medications, of non-prescribed supplements and other substances, as part of the history. In addition, the case highlights the potential for highly debilitating adverse effects from using DMSO.

Indexed as

Dimethyl SulfoxideDrug MisuseSelf-ManagementAgedCerebral HemorrhageDepressionHumansMalePainRecurrenceTomography, X-Ray ComputedDimethyl Sulfoxidedrugs misuse (including addiction)neurology (drugs and medicines)psychiatry (drugs and medicines)safetystroke

Identifiers

PMID33541956
PMCPMC7868225
OpenAlexW3128204106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.