Evidence map›Paper›PMID 33541688›Full record

ArticleAmerican journal of surgery2021

Total pancreatectomy with islet autotransplantation reduces resource utilization in pediatric patients.

Al-Faraaz Kassam, Alexander R Cortez, Michael E Johnston, Huaiyu Zang, Lin Fei, Tom K Lin, Maisam Abu-El-Haija, Jaimie D Nathan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Al-Faraaz KassamCincinnati Children's Hospital Medical Center, Division of Pediatric General and Thoracic Surgery, Cincinnati, OH, USA; University of Cincinnati Medical Center, Department of Surgery, Cincinnati, OH, USA.
Alexander R CortezCincinnati Children's Hospital Medical Center, Division of Pediatric General and Thoracic Surgery, Cincinnati, OH, USA; University of Cincinnati Medical Center, Department of Surgery, Cincinnati, OH, USA.
Michael E JohnstonCincinnati Children's Hospital Medical Center, Division of Pediatric General and Thoracic Surgery, Cincinnati, OH, USA; University of Cincinnati Medical Center, Department of Surgery, Cincinnati, OH, USA.
Huaiyu ZangCincinnati Children's Hospital Medical Center, Division of Biostatistics and Epidemiology, Cincinnati, OH, USA.
Lin FeiCincinnati Children's Hospital Medical Center, Division of Biostatistics and Epidemiology, Cincinnati, OH, USA.
Tom K LinCincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati, OH, USA; University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati, OH, USA.
Maisam Abu-El-HaijaCincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati, OH, USA; University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati, OH, USA.
Jaimie D NathanCincinnati Children's Hospital Medical Center, Division of Pediatric General and Thoracic Surgery, Cincinnati, OH, USA; University of Cincinnati Medical Center, Department of Surgery, Cincinnati, OH, USA. Electronic address: Jaimie.Nathan@cchmc.org.
Cincinnati Children's Hospital Medical Center · US

Funding

Predicting Severity and Improving the Outcomes of Pediatric PancreatitisK23DK118190 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI ABU-EL-HAIJA, MAISAM · 2018 to 2022
$947k
NIDDK NIH HHS K23 DK118190
6 · The paper itself

Abstract

backgroundChronic pancreatitis (CP) is associated with poor quality of life. Total pancreatectomy with islet autotransplantation (TPIAT) has traditionally been reserved for patients with refractory disease. We hypothesized TPIAT would lead to decreased costs and resource utilization after operation in children.

methodsRetrospective review of 39 patients who underwent TPIAT at a single children's hospital was performed. All inpatient admissions, imaging, endoscopic procedures, and operations were recorded for the year prior to and following operation. Costs were determined from Centers for Medicare and Medicaid Services.

resultsMedian hospital admissions before operation was 5 (IQR:2-7) and decreased to 2 (IQR:1-3) after (p < 0.01). Median total cost for the year before operation was $36,006 (IQR:$19,914-$47,680), decreasing to $24,900 postoperatively (IQR:$17,432-$44,005, p = 0.03). Removing cost of TPIAT itself, total cost was further reduced to $10,564 (IQR:$3096-$29,669, p < 0.01).

conclusionIn children with debilitating CP, TPIAT has favorable impact on cost reduction, hospitalizations, and invasive procedures. Early intervention at a specialized pancreas center of excellence should be considered to decrease future resource utilization and costs among children.

Indexed as

Analgesics, OpioidChildCost ControlFemaleHealth ResourcesHumansIslets of Langerhans TransplantationMaleMarkov ChainsPancreatectomyPancreatitis, ChronicPatient ReadmissionRetrospective StudiesTransplantation, AutologousAnalgesics, OpioidInsulinOpioidPancreatitisResource utilizationTPIAT

Identifiers

PMID33541688
PMCPMC10123923
OpenAlexW3121264509

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.