Evidence map›Paper›PMID 33541403›Full record

ArticleBreast cancer research : BCR2021

Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients.

Lihua Shang, Masaya Hattori, Gini Fleming, Nora Jaskowiak, Donald Hedeker, Olufunmilayo I Olopade, Dezheng Huo

Abstract read
In one paragraph

Article in Breast cancer research : BCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Exploring the multifaceted role of obesity in breast cancer progression.Frontiers in cell and developmental biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lihua ShangDepartment of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China.
Masaya HattoriDepartment of Breast Oncology, Aichi Cancer Center, Nagoya, Japan.
Gini FlemingSection of Hematology and Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA.
Nora JaskowiakDepartment of Surgery, University of Chicago, Chicago, IL, USA.
Donald HedekerDepartment of Public Health Sciences, University of Chicago, 5841 S. Maryland Avenue, MC 2000, Chicago, IL, 60637, USA.
Olufunmilayo I OlopadeSection of Hematology and Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA.
Dezheng HuoSection of Hematology and Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA. dhuo@health.bsd.uchicago.edu.ORCID 0000-0002-4041-1678

Funding

UChicago Interdisciplinary Cancer Health Disparities SPOREP20CA233307 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F. · 2018 to 2020
$3.4M
NCI NIH HHS P20 CA233307
6 · The paper itself

Abstract

purposeTo evaluate weight change patterns over time following the diagnosis of breast cancer and to examine the association of post-diagnosis weight change and survival outcomes in Black and White patients.

methodsThe study included 2888 women diagnosed with non-metastatic breast cancer in 2000-2017 in Chicago. Longitudinal repeated measures of weight and height were collected, along with a questionnaire survey including questions on body size. Multilevel mixed-effects models were used to examine changes in body mass index (BMI). Delayed entry Cox proportional hazards models were used to investigate the impacts of changing slope of BMI on survival outcomes.

resultsAt diagnosis, most patients were overweight or obese with a mean BMI of 27.5 kg/m

conclusionBMI loss is a strong predictor of worse breast cancer outcomes. Growing prevalence of obesity may hide diagnosis of cancer cachexia, which can occur in a large proportion of breast cancer patients long before death.

Indexed as

Black PeopleBody WeightWhite PeopleAdultAgedAged, 80 and overBody Mass IndexBody Weights and MeasuresBreast NeoplasmsCase-Control StudiesComorbidityFemaleHumansMiddle AgedNeoplasm GradingNeoplasm StagingBody mass indexBreast cancerPrognosisRacial disparitiesWeight change

Identifiers

PMID33541403
PMCPMC7863526

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.