Evidence map›Paper›PMID 33541205›Full record

ArticleRNA biology2021

Structural studies of RNase M5 reveal two-metal-ion supported two-step dsRNA cleavage for 5S rRNA maturation.

Stephanie Oerum, Marjorie Catala, Maxime Bourguet, Laetitia Gilet, Pierre Barraud, Sarah Cianférani, Ciarán Condon, Carine Tisné

Abstract read
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Specificity and mechanism of tRNA cleavage by the AriB Toprim nuclease of the PARIS bacterial immune system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie OerumExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.ORCID 0000-0001-9525-7295
Marjorie CatalaExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.
Maxime BourguetLaboratoire de Spectrométrie de Masse BioOrganique, CNRS, IPHC UMR 7178, Université de Strasbourg, Strasbourg, France.
Laetitia GiletExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.
Pierre BarraudExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.ORCID 0000-0003-4460-8360
Sarah CianféraniLaboratoire de Spectrométrie de Masse BioOrganique, CNRS, IPHC UMR 7178, Université de Strasbourg, Strasbourg, France.ORCID 0000-0003-4013-4129
Ciarán CondonExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.ORCID 0000-0002-2199-9621
Carine TisnéExpression Génétique Microbienne, UMR 8261, CNRS, Institut de Biologie Physico-Chimique (IBPC), Université de Paris, Paris, France.ORCID 0000-0001-5534-4650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All species transcribe ribosomal RNA in an immature form that requires several enzymes for processing into mature rRNA. The number and types of enzymes utilized for these processes vary greatly between different species. In low G + C Gram-positive bacteria including

Indexed as

Amino Acid SequenceBacillus subtilisEndoribonucleasesGeobacillus stearothermophilusMagnesiumNucleic Acid ConformationRibosomesRNA, Double-StrandedRNA PrecursorsRNA, Ribosomal, 5SSubstrate SpecificityEndoribonucleasesMagnesiumribonuclease M5RNA, Double-StrandedRNA PrecursorsRNA, Ribosomal, 5S5SM5maturationmechanismprocessingribonucleaseRibosomal RNAToprim domain

Identifiers

PMID33541205
PMCPMC8582995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.