Evidence map›Paper›PMID 33540911›Full record

ArticleInternational journal of environmental research and public health2021

The Relationship of Race, Psychosocial Stress and Resiliency Indicators to Neurocognitive Impairment among Older Americans Enrolled in the Health and Retirement Survey: A Cross-Sectional Study.

Allan K Nkwata, Ming Zhang, Xiao Song, Bruno Giordani, Amara E Ezeamama

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cerebral arteriolosclerosis, lacunar infarcts, and cognition in older Black adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Prevalence of suspected dementia in a sample of adults living in Kinshasa-Democratic Republic of the Congo.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Allan K NkwataDepartment of Epidemiology and Biostatistics, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-9412-6370
Ming ZhangDepartment of Epidemiology and Biostatistics, University of Georgia, Athens, GA 30602, USA.
Xiao SongDepartment of Epidemiology and Biostatistics, University of Georgia, Athens, GA 30602, USA.
Bruno GiordaniDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA.
Amara E EzeamamaDepartment of Psychiatry, College of Osteopathic Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-2164-8802
University of Georgia · USMichigan State University · USUniversity of Michigan · US

Funding

Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
NIA NIH HHS P30 AG053760
6 · The paper itself

Abstract

backgroundRace/ethnicity, toxic stress (TS), resilience-promoting factors (RPFs), and their interactions were investigated in relationship to neurocognitive impairment (NI) in a nationally representative sample of adult Americans ≥50 years enrolled in the Health and Retirement Study (HRS) between 2012 and 2014.

methodsNI was defined as physician diagnosis of Alzheimer's disease/dementia or HRS total cognition score ≤ 10. Race/ethnicity (i.e., African American, White, or Other), TS (i.e., everyday discrimination and chronic stressors), and mastery (as indicator of RPF) were self-reported. Multivariable logistic regression models estimated race-, TS-, RPF-associated odds ratios (ORs), and 95% confidence intervals (CI) for NI adjusting for socio-demographic confounders.

results6317 respondents interviewed between the years 2012 and 2014, age range 55-104 years old, 83% White, 13% Black and 4% Other race were included in the study. Chronic stress (OR = 1.88, 95% CI: 1.42-2.48), discrimination (OR = 3.31, 95% CI: 2.12-5.19) and low mastery (OR = 1.85, 95% CI: 1.38-2.48) were each associated with higher NI risk while low mastery was associated with higher NI risk in discrimination and race/ethnicity dependent manner. Specifically, low mastery-associated risk for NI was evident among adults that denied experiencing discrimination (OR = 2.01, 95% CI: 1.51-2.68), but absent among those that experienced discrimination (OR = 0.72, 95% CI: 0.32-1.62). Further, AA race was associated with NI risk but only among adults with high mastery (OR = 2.00, 95% CI: 1.20-3.35).

conclusionsDiscrimination, chronic stress, and low mastery were associated with worse cognition. Persisting cognitive disadvantage for AA vs. White/Other race only among high mastery adults suggests that adverse social experiences may counteract mastery-associated cognitive benefits among AA population. TS reduction through policies that promote equal treatment by race/ethnicity in social life, health, justice, and economic systems may promote successful cognitive aging.

Indexed as

Black or African AmericanRetirementAdultAgedAged, 80 and overCross-Sectional StudiesEthnicityHispanic or LatinoHumansMiddle AgedStress, PsychologicalUnited Stateseveryday discriminationminority raceneurocognitive impairmentolder Americansresilience promoting factorstoxic stress

Identifiers

PMID33540911
PMCPMC7908633
OpenAlexW3128563272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.