Evidence map›Paper›PMID 33540888›Full record

ArticleInternational journal of molecular sciences2021

Distinct Effects of

Edina Pandur, Kitti Tamási, Ramóna Pap, Gergely Jánosa, Katalin Sipos

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in microbiology · 2023
    Article
  5. Article
  6. Article
  7. The Role of Iron inFrontiers in cell and developmental biology · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Edina PandurDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.ORCID 0000-0001-5012-3242
Kitti TamásiDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Ramóna PapDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Gergely JánosaDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Katalin SiposDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.ORCID 0000-0002-6706-2682
University of Pecs · HU

Funding

Comprehensive Development for Implementing Smart Specialization Strategies at the University of Pécs EFOP-3.6.1.-16-2016-00004National Research, Development and Innovation Office 2020-4.1.1.-TKP2020
6 · The paper itself

Abstract

Macrophages are essential immune cells of the innate immune system. They participate in the development and regulation of inflammation. Macrophages play a fundamental role in fighting against bacterial infections by phagocytosis of bacteria, and they also have a specific role in immunomodulation by secreting pro-inflammatory cytokines. In bacterial infection, macrophages decrease the serum iron concentration by removing iron from the blood, acting as one of the most important regulatory cells of iron homeostasis. We examined whether the Gram-positive and Gram-negative cell wall components from various bacterial strains affect the cytokine production and iron transport, storage and utilization of THP-1 monocytes in different ways. We found that

Indexed as

Biological TransportCell WallChemokine CX3CL1CX3C Chemokine Receptor 1CytokinesCytosolEscherichia coliFerritinsHeme Oxygenase-1HepcidinsHumansIronLipopolysaccharidesMitochondriaNeoplasm ProteinsOxidoreductasesChemokine CX3CL1CX3C Chemokine Receptor 1CX3CL1 protein, humanCX3CR1 protein, humanCytokinesFerritinsFTH1 protein, humanHeme Oxygenase-1HepcidinsHMOX1 protein, humanIronLipopolysaccharideslipoteichoic acidNeoplasm ProteinsOxidoreductasesRNA, MessengerRNA, NeoplasmTeichoic Acidscytokineferroportinfractalkineheme oxygenasehepcidininflammationironmacrophage

Identifiers

PMID33540888
PMCPMC7867333
OpenAlexW3126989941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.