Evidence map›Paper›PMID 33540773›Full record

GuidelineCancers2021

Bringing Onco-Innovation to Europe's Healthcare Systems: The Potential of Biomarker Testing, Real World Evidence, Tumour Agnostic Therapies to Empower Personalised Medicine.

Denis Horgan, Gennaro Ciliberto, Pierfranco Conte, Giuseppe Curigliano, Luis Seijo, Luis M Montuenga, Marina Garassino, Frederique Penault-Llorca, Fabrizia Galli, Isabelle Ray-Coquard and 20 more

Open access · goldAbstract readGuideline
In one paragraph

Guideline in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 8 countries.

Denis HorganEuropean Alliance for Personalized Medicine, Avenue de l'Armee/ Legerlaan 10, 1040 Brussels, Belgium.
Gennaro CilibertoIRCCS Istituto Nazionale Tumori "Regina Elena", Via Elio Chianesi, 53, 00128 Rome, Italy.ORCID 0000-0003-2851-8605
Pierfranco ConteDipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0002-5210-5344
Giuseppe CuriglianoDepartment of Oncology and Hemato-Oncology, University of Milano and European Institute of Oncology, IRCCS, 20139 Milano, Italy.
Luis SeijoDepartamento de Química, Clinica Universidad de Navarra, Calle Marquesado de Sta. Marta, 1, 28027 Madrid, Spain.
Luis M MontuengaCiber Enfermedades Respiratorias (CIBERES), Av. de Monforte de Lemos, 3-5, 28029 Madrid, Spain.ORCID 0000-0002-8739-1387
Marina GarassinoS.S. Oncologia Medica Toraco Polmonare, Fondazione IRCCS Istituto Nazionale dei Tumori Via Giacomo Venezian, 1, 20133 Milano, Italy.
Frederique Penault-LlorcaDepartment of Pathology and Tumor Biology, University of Clermont-Auvergne, 49 bd François Mitterrand, 63001 Clermont-Ferrand, France.
Fabrizia GalliAssociazione aBRCAdaBRA Onlus Via Volontari Italiani del Sangue, 32, 90128 Palermo, Italy.
Isabelle Ray-CoquardMedical Oncology Department, Centre Leon Bérard & Université Claude Bernard Lyon, 69008 Lyon, France.ORCID 0000-0003-2472-8306
Denis QuerleuSurgery Department, Institut Bergonié Cancer Center, Centre Léon Bérard Cheney D- 2 ème étage -28 Rue Laennec, 69373 Lyon, France.
Peter RiegmanDepartment of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, Be 235b, Dr Molwaterplein 50, 3015 Rotterdam, The Netherlands.
Keith KerrDepartment of Pathology, University of Aberdeen, King's College, Aberdeen AB24 3FX, UK.
Hein Van PoppelDepartment of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
Anders BjartellDepartment of Urology, Skane University Hospital, Box 117, 221 00 Lund, Sweden.
Giovanni Codacci-PisanelliDepartment of Medical and Surgical Sciences and Biotechnology, University of Rome, "la Sapienza", Piazzale Aldo Moro, 5, 00185 Roma, Italy.ORCID 0000-0003-4662-7944
Jasmina Koeva-BalabanovaBulgarian Association for Personalised Medicine, 45 Bacho Kiro Str., 1202 Sofia, Bulgaria.
Angelo ParadisoScientific Directorate, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124 Bari, Italy.ORCID 0000-0001-6495-2295
Zorana MaravicDigestive Cancers Europe, Rue de la Loi 235, 1040 Brussels, Belgium.
Vassiliki FotakiDigestive Cancers Europe, Rue de la Loi 235, 1040 Brussels, Belgium.
Nuria MalatsSpanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro, 3, 28029 Madrid, Spain.ORCID 0000-0003-2538-3784
Chiara BerniniEuropean Alliance for Personalized Medicine, Avenue de l'Armee/ Legerlaan 10, 1040 Brussels, Belgium.
Simonetta BuglioniIRCCS Istituto Nazionale Tumori "Regina Elena", Via Elio Chianesi, 53, 00128 Rome, Italy.
Alastair KentIndependent Patient Advocate, 14 Farthing Road Downham Market, Norfolk PE38 0AF, UK.
Elisabetta MunzoneDivision of Medical Senology, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, 20141 Milano, Italy.ORCID 0000-0003-3371-3878
Ivica BelinaKUZ-Coalition of Association in Healthcare, Trpimirova 11, 10000 Zagreb, Croatia.
Jan Van MeerbeeckThoracic Oncology-MOCA, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium.
Michael DuffyUCD School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.ORCID 0000-0002-9259-6619
Beata JagielskaMaria Skłodowska-Curie Institute of Oncology, Wawelska 15 B, 00-001 Warszawa, Poland.
Ettore CapoluongoDepartment of Molecular Medicine and Medical Biotechnologies, University of Naples Federico II, 80131 Naples, Italy.
European Organisation for Research and Treatment of Cancer · BEIstituti di Ricovero e Cura a Carattere Scientifico · ITAntwerp University Hospital · BECeinge Biotecnologie Avanzate (Italy) · ITCentre Léon Bérard · FRCentro de Investigación Biomédica en Red de Cáncer · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESFondazione IRCCS Istituto Nazionale dei Tumori · ITIstituto Tumori Bari · ITKU Leuven · BERipamonti · ITSapienza University of Rome · ITSkåne University Hospital · SESpanish National Cancer Research Centre · ESThe Maria Sklodowska-Curie National Research Institute of Oncology · PLUniversité Claude Bernard Lyon 1 · FRUniversité Clermont Auvergne · FRUniversity College Dublin · IEUniversity of Aberdeen · GBUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid and continuing advances in biomarker testing are not being matched by uptake in health systems, and this is hampering both patient care and innovation. It also risks costing health systems the opportunity to make their services more efficient and, over time, more economical. The potential that genomics has brought to biomarker testing in diagnosis, prediction and research is being realised, pre-eminently in many cancers, but also in an ever-wider range of conditions-notably

Indexed as

biomarkerscancersEurope’s Healthcare SystemsHRDoncogenomics

Identifiers

PMID33540773
PMCPMC7867284
OpenAlexW3055391720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.