Evidence map›Paper›PMID 33540764›Full record

ArticlePharmaceutics2021

Nebuliser Type Influences Both Patient-Derived Bioaerosol Emissions and Ventilation Parameters during Mechanical Ventilation.

Mary Joyce, James A McGrath, Marc Mac Giolla Eain, Andrew O'Sullivan, Miriam Byrne, Ronan MacLoughlin

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Nebuliser therapy in critical care: The past, present and future.Journal of the Intensive Care Society · 2024
    Review
  7. AnFrontiers in medicine · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. AnDrug delivery · 2021
    Article
  14. Article
  15. Cellular Therapy for the Treatment of Paediatric Respiratory Disease.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mary JoyceAerogen Limited, Galway Business Park, H91 HE94 Galway, Ireland.
James A McGrathSchool of Physics & Ryan Institute's Centre for Climate and Air Pollution Studies, National University of Ireland Galway, H91 CF50 Galway, Ireland.ORCID 0000-0002-9832-370X
Marc Mac Giolla EainAerogen Limited, Galway Business Park, H91 HE94 Galway, Ireland.
Andrew O'SullivanAerogen Limited, Galway Business Park, H91 HE94 Galway, Ireland.ORCID 0000-0002-5434-1260
Miriam ByrneSchool of Physics & Ryan Institute's Centre for Climate and Air Pollution Studies, National University of Ireland Galway, H91 CF50 Galway, Ireland.
Ronan MacLoughlinAerogen Limited, Galway Business Park, H91 HE94 Galway, Ireland.ORCID 0000-0002-3164-1607
Aerogen (Ireland) · IEOllscoil na Gaillimhe – University of Galway · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 may lead to serious respiratory complications which may necessitate ventilatory support. There is concern surrounding potential release of patient-derived bioaerosol during nebuliser drug refill, which could impact the health of caregivers. Consequently, mesh nebulisers have been recommended by various clinical practice guidelines. Currently, there is a lack of empirical data describing the potential for release of patient-derived bioaerosol during drug refill. This study examined the release of simulated patient-derived bioaerosol, and the effect on positive end expiratory pressure during nebuliser refill during mechanical ventilation of a simulated patient. During jet nebuliser refill, the positive end expiratory pressure decreased from 4.5 to 0 cm H

Indexed as

aerosol generating procedurebioaerosolCOVID-19dispersionexposureinfectious diseasejet nebulisermechanical ventilationvibrating mesh nebuliser

Identifiers

PMID33540764
PMCPMC7912998
OpenAlexW3128789620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.