Evidence map›Paper›PMID 33540763›Full record

ArticleInternational journal of environmental research and public health2021

A Clinical-Epidemiological and Geospatial Study of Tuberculosis in a Neglected Area in the Amazonian Region Highlights the Urgent Need for Control Measures.

Cristal Ribeiro Mesquita, Emilyn Costa Conceição, Lúcia Helena Martins Tavares Monteiro, Odinea Maria da Silva, Luana Nepomuceno Gondim Costa Lima, Rafael Aleixo Coelho de Oliveira, Artemir Coelho de Brito, Ricardo José de Paula Souza E Guimarães, Karla Valéria Batista Lima

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Cristal Ribeiro MesquitaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil.ORCID 0000-0002-1321-5719
Emilyn Costa ConceiçãoPrograma de Pós-Graduação em Pesquisa Clínica em Doenças Infecciosas do Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil, 4365, Rio de Janeiro 21040-900, Brazil.ORCID 0000-0002-7445-6620
Lúcia Helena Martins Tavares MonteiroSecretaria de Saúde do Estado do Pará-SESPA, Av. João Paulo II, 602, Belem 66087-048, Brazil.
Odinea Maria da SilvaSecretaria de Saúde do Estado do Pará-SESPA, Av. João Paulo II, 602, Belem 66087-048, Brazil.
Luana Nepomuceno Gondim Costa LimaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil.
Rafael Aleixo Coelho de OliveiraPrograma de Pós-Graduação em Saúde, Ambiente e Sociedade, Universidade Federal do Pará, Rua Augusto Corrêa, Belem 66075-110, Brazil.
Artemir Coelho de BritoCoordenação Geral de Vigilância das Doenças de Transmissão Respiratória de Condições Crônicas, Av. Brasil, 4365, Rio de Janeiro 21040-900, Brazil.
Ricardo José de Paula Souza E GuimarãesPrograma de Pós-Graduação em Epidemiologia e Vigilância em Saúde, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil.ORCID 0000-0002-5767-4765
Karla Valéria Batista LimaPrograma de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil.ORCID 0000-0001-5807-0392
Universidade do Estado do Pará · BRInstituto Evandro Chagas · BRSecretaria da Saúde · BRUniversidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is an infectious communicable disease, which despite global efforts, still needs special attention in regions with difficult access. This study aims to describe the spatial and epidemiological trends of TB incidences from 2013 to 2018 in Marajó Island, the Amazonian region, Pará, Brazil. We have obtained secondary data from the Brazilian TB databases and performed geospatial and statistical analyses on the data for new TB cases, relapses, and re-admissions. From 2013 to 2018, 749 new cases were reported, in which the diagnostics (culture) was not performed for 652 (87.2%) patient samples, the drug resistance test (DST) was performed for nine (1.2%) samples, and one (0.13%) was multidrug-resistant TB (MDR-TB). The rapid molecular testing (RMT) was performed on 40 (5.3%) patient samples, with results indicating that eight (20%) were susceptible to rifampicin and two (5%) were rifampicin resistant. Overall, the cure rate was 449 (66.7%), while relapses and re-admissions were 41 and 44, respectively. On the geospatial distribution, the municipality of Soure stands out with a high number of incidences, relapses, and re-admissions. Spatially, the eight MDR cases were randomly distributed. Our data highlight the urgent need for TB control measures in this region, by introducing the Xpert-Ultra

Indexed as

Antibiotics, AntitubercularMycobacterium tuberculosisTuberculosisBrazilHumansNeoplasm Recurrence, LocalSensitivity and SpecificityAntibiotics, AntitubercularBrazilepidemiologygeospatial distributionstate of Parátuberculosis

Identifiers

PMID33540763
PMCPMC7908568
OpenAlexW3128481378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.