Evidence map›Paper›PMID 33540754›Full record

ArticleMolecules (Basel, Switzerland)2021

NMR and LC-MS-Based Metabolomics to Study Osmotic Stress in Lignan-Deficient Flax.

Kamar Hamade, Ophélie Fliniaux, Jean-Xavier Fontaine, Roland Molinié, Elvis Otogo Nnang, Solène Bassard, Stéphanie Guénin, Laurent Gutierrez, Eric Lainé, Christophe Hano and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Review
  6. Compound-Specific 1DACS omega · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Kamar HamadeUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.
Ophélie FliniauxUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.
Jean-Xavier FontaineUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.ORCID 0000-0001-8189-9238
Roland MoliniéUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.ORCID 0000-0003-4399-8838
Elvis Otogo NnangUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.
Solène BassardUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.
Stéphanie GuéninCRRBM, University of Picardie Jules Verne, 80000 Amiens, France.
Laurent GutierrezCRRBM, University of Picardie Jules Verne, 80000 Amiens, France.
Eric LainéUSC INRAE 1328, Laboratoire LBLGC, Antenne Scientifique Universitaire de Chartres, University of Orleans, 28000 Chartres, France.
Christophe HanoUSC INRAE 1328, Laboratoire LBLGC, Antenne Scientifique Universitaire de Chartres, University of Orleans, 28000 Chartres, France.ORCID 0000-0001-9938-0151
Serge PilardPlateforme Analytique, University of Picardie Jules Verne, 80000 Amiens, France.ORCID 0000-0002-9167-526X
Akram HijaziPlatform for Research and Analysis in Environmental Sciences (PRASE), Lebanese University, Beirut 6573, Lebanon.ORCID 0000-0003-4984-8531
Assem El KakLaboratoire de Biotechnologie des Substances Naturelles et Produits de Santé (BSNPS), Lebanese University, Beirut 6573, Lebanon.
François MesnardUMRT INRAE 1158 BioEcoAgro, Laboratoire BIOPI, University of Picardie Jules Verne, 80000 Amiens, France.
École Polytechnique · FRUniversité de Picardie Jules Verne · FRLebanese University · LBUniversité d'Orléans · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lignans, phenolic plant secondary metabolites, are derived from the phenylpropanoid biosynthetic pathway. Although, being investigated for their health benefits in terms of antioxidant, antitumor, anti-inflammatory and antiviral properties, the role of these molecules in plants remains incompletely elucidated; a potential role in stress response mechanisms has been, however, proposed. In this study, a non-targeted metabolomic analysis of the roots, stems, and leaves of wild-type and PLR1-RNAi transgenic flax, devoid of (+) secoisolariciresinol diglucoside ((+) SDG)-the main flaxseed lignan, was performed using

Indexed as

Chromatography, LiquidMagnetic Resonance SpectroscopyMass SpectrometryMetabolomicsOsmotic PressureFlaxLignansPhenotypeLignans1H-NMRflaxLC-MSlignansmetabolomicsosmotic stressRNA interferencesecoisolariciresinol

Identifiers

PMID33540754
PMCPMC7867241
OpenAlexW3127163006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.