Evidence map›Paper›PMID 33540713›Full record

ArticleViruses2021

The SARS-CoV-2-Inactivating Activity of Hydroxytyrosol-Rich Aqueous Olive Pulp Extract (HIDROX

Yohei Takeda, Dulamjav Jamsransuren, Sachiko Matsuda, Roberto Crea, Haruko Ogawa

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Rapid Virucidal Activity of JapaneseApplied and environmental microbiology · 2023
    Article
  8. COVID-19 Therapeutic Potential of Natural Products.International journal of molecular sciences · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Antiviral activity of medicinal plant-derived products against SARS-CoV-2.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  14. Review
  15. Article
  16. Prospects of Coffee Leaf against SARS-CoV-2 Infection.International journal of biological sciences · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yohei TakedaResearch Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan.
Dulamjav JamsransurenDepartment of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan.
Sachiko MatsudaDepartment of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan.
Roberto CreaOliphenol LLC., 26225 Eden Landing Road, Suite C, Hayward, CA 94545, USA.
Haruko OgawaDepartment of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido 080-8555, Japan.ORCID 0000-0001-5889-499X
Obihiro University of Agriculture and Veterinary Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally. Although measures to control SARS-CoV-2, namely, vaccination, medication, and chemical disinfectants are being investigated, there is an increase in the demand for auxiliary antiviral approaches using natural compounds. Here we have focused on hydroxytyrosol (HT)-rich aqueous olive pulp extract (HIDROX

Indexed as

OleaAdministration, TopicalAnimalsAntiviral AgentsCarbohydratesChlorocebus aethiopsCoronavirus Nucleocapsid ProteinsGenome, ViralGlycosylationMicrobial Sensitivity TestsPhenylethyl AlcoholPhosphoproteinsPlant ExtractsSARS-CoV-2Skin CreamSpike Glycoprotein, Coronavirus3,4-dihydroxyphenylethanolAntiviral AgentsCarbohydratesCoronavirus Nucleocapsid Proteinsnucleocapsid phosphoprotein, SARS-CoV-2Phenylethyl AlcoholPhosphoproteinsPlant ExtractsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2aqueous olive pulp extracthydroxytyrosolnatural-derived materialsevere acute respiratory syndrome coronavirus 2topical applicationvirus inactivation

Identifiers

PMID33540713
PMCPMC7913061
OpenAlexW3126932844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.