Evidence map›Paper›PMID 33540662›Full record

ArticleViruses2021

Human Respiratory Syncytial Virus Infection in a Human T Cell Line Is Hampered at Multiple Steps.

Ricardo de Souza Cardoso, Rosa Maria Mendes Viana, Brenda Cristina Vitti, Ana Carolina Lunardello Coelho, Bruna Laís Santos de Jesus, Juliano de Paula Souza, Marjorie Cornejo Pontelli, Tomoyuki Murakami, Armando Morais Ventura, Akira Ono and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Novel Wide-Spectrum Virucidal Lipid Nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ricardo de Souza CardosoDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.ORCID 0000-0003-2858-2076
Rosa Maria Mendes VianaDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.ORCID 0000-0001-5722-4142
Brenda Cristina VittiDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Ana Carolina Lunardello CoelhoDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Bruna Laís Santos de JesusDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Juliano de Paula SouzaDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Marjorie Cornejo PontelliDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Tomoyuki MurakamiDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Armando Morais VenturaDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo 05508-000, Brazil.
Akira OnoDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.ORCID 0000-0001-7841-851X
Eurico ArrudaDepartment of Cell and Molecular Biology, School of Medicine of Ribeirao Preto, University of Sao Paulo, São Paulo 14049-900, Brazil.
Universidade de São Paulo · BRUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory disease in children. The main targets of HRSV infection are epithelial cells of the respiratory tract, and the great majority of the studies regarding HRSV infection are done in respiratory cells. Recently, the interest on respiratory virus infection of lymphoid cells has been growing, but details of the interaction of HRSV with lymphoid cells remain unknown. Therefore, this study was done to assess the relationship of HRSV with A3.01 cells, a human CD4

Indexed as

Cell LineHumansRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsT-LymphocytesViral Fusion ProteinsVirus AssemblyVirus ReplicationViral Fusion ProteinsHRSV entryHRSV filament formationHRSV inclusion body-associated granules (IBAG′s)HRSV intracellular traffickingHRSV low protein productionHRSV R18 fusion assayhuman respiratory syncytial virus (HRSV) infection in T-cell lineinefficient HRSV replication A3.01

Identifiers

PMID33540662
PMCPMC7913106
OpenAlexW3127720977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.