Evidence map›Paper›PMID 33540660›Full record

ArticleDiagnostics (Basel, Switzerland)2021

End-to-End, Pixel-Wise Vessel-Specific Coronary and Aortic Calcium Detection and Scoring Using Deep Learning.

Gurpreet Singh, Subhi J Al'Aref, Benjamin C Lee, Jing Kai Lee, Swee Yaw Tan, Fay Y Lin, Hyuk-Jae Chang, Leslee J Shaw, Lohendran Baskaran, On Behalf Of The Credence And Iconic Investigators

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
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  6. Article
  7. Review
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  10. Article
  11. Calcium scoring in low-dose ungated chest CT scans using convolutional long-short term memory networks.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gurpreet SinghDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
Subhi J Al'ArefDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
Benjamin C LeeDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
Jing Kai LeeDepartment of Cardiovascular Medicine, National Heart Centre, Singapore 169609, Singapore.
Swee Yaw TanDepartment of Cardiovascular Medicine, National Heart Centre, Singapore 169609, Singapore.
Fay Y LinDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
Hyuk-Jae ChangDivision of Cardiology, Severance Cardiovascular Hospital, Integrative Cardiovascular Imaging Center, Yonsei University College of Medicine, Seoul 03722, Korea.
Leslee J ShawDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
Lohendran BaskaranDalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, NY 10021, USA.
On Behalf Of The Credence And Iconic Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional scoring and identification methods for coronary artery calcium (CAC) and aortic calcium (AC) result in information loss from the original image and can be time-consuming. In this study, we sought to demonstrate an end-to-end deep learning model as an alternative to the conventional methods. Scans of 377 patients with no history of coronary artery disease (CAD) were obtained and annotated. A deep learning model was trained, tested and validated in a 60:20:20 split. Within the cohort, mean age was 64.2 ± 9.8 years, and 33% were female. Left anterior descending, right coronary artery, left circumflex, triple vessel, and aortic calcifications were present in 74.87%, 55.82%, 57.41%, 46.03%, and 85.41% of patients respectively. An overall Dice score of 0.952 (interquartile range 0.921, 0.981) was achieved. Stratified by subgroups, there was no difference between male (0.948, interquartile range 0.920, 0.981) and female (0.965, interquartile range 0.933, 0.980) patients (

Indexed as

coronary artery calciumdeep learningmachine learning

Identifiers

PMID33540660
PMCPMC7913112

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.