ReviewInternational journal of molecular sciences2021
Relative Contribution of Proprioceptive and Vestibular Sensory Systems to Locomotion: Opportunities for Discovery in the Age of Molecular Science.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07568808 (Comparative Effects of Core Stabilization Exercises and Kinesthetic Training in Diplegic Cerebral Palsy), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of Core Stabilization Exercises and Kinesthetic Training in Diplegic Cerebral Palsy
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Identifying Therapeutic Targets for Amyotrophic Lateral Sclerosis Through Modeling of Multi-Omics Data.International journal of molecular sciences · 2025Article
- Optimizing noisy galvanic vestibular stimulation (nGVS) for postural control: methodological considerations when individualizing the signal for people with bilateral vestibulopathy.Frontiers in neurology · 2025Article
- Article
- Dynamic Changes in Hindlimb Motor Cortex Neurons during Simulated Weightlessness Revealed by Miniature 2-Photon Microscopy.Research (Washington, D.C.) · 2025Article
- A model linking emotional dysregulation in neurodivergent people to the proprioceptive impact of joint hypermobility.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Sensory feedback and central neuronal interactions in mouse locomotion.Royal Society open science · 2024Article
- Turning speed as a more responsive metric of age-related decline in mobility: A comparative study with gait speed.Clinical biomechanics (Bristol, Avon) · 2024Article
- Functional organization of vestibulospinal inputs responsible for tail postural control in larvalFrontiers in neurology · 2024Article
- Sensory Feedback and Central Neuronal Interactions in Mouse Locomotion.bioRxiv : the preprint server for biology · 2023Article
- Gate control of sensory neurotransmission in peripheral ganglia by proprioceptive sensory neurons.Brain : a journal of neurology · 2023Article
- The molecular athlete: exercise physiology from mechanisms to medals.Physiological reviews · 2023Review
- Brainstem neural mechanisms controlling locomotion with special reference to basal vertebrates.Frontiers in neural circuits · 2023Review
- Exploring the Nexus of lower extremity proprioception and postural stability in older adults with osteoporosis: a cross-sectional investigation.Frontiers in public health · 2023Article
- Adult spinal Dmrt3 neurons receive direct somatosensory inputs from ipsi- and contralateral primary afferents and from brainstem motor nuclei.The Journal of comparative neurology · 2023Article
- The Impact of Activity-Based Interventions on Neuropathic Pain in Experimental Spinal Cord Injury.Cells · 2022Review
- Immersive Virtual Reality and Vestibular Rehabilitation in Multiple Sclerosis: Case Report.JMIR serious games · 2022Article
- Phase-dependent modulation of the vestibular-cerebellar networkFrontiers in neuroscience · 2022Article
- Thorax-Segment- and Leg-Segment-Specific Motor Control for Adaptive Behavior.Frontiers in physiology · 2022Article
- Influence of Controlled Stomatognathic Motor Activity on Sway, Control and Stability of the Center of Mass During Dynamic Steady-State Balance-An Uncontrolled Manifold Analysis.Frontiers in human neuroscience · 2022Article
- How Does the Central Nervous System for Posture and Locomotion Cope With Damage-Induced Neural Asymmetry?Frontiers in systems neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Locomotion is a fundamental animal behavior required for survival and has been the subject of neuroscience research for centuries. In terrestrial mammals, the rhythmic and coordinated leg movements during locomotion are controlled by a combination of interconnected neurons in the spinal cord, referred as to the central pattern generator, and sensory feedback from the segmental somatosensory system and supraspinal centers such as the vestibular system. How segmental somatosensory and the vestibular systems work in parallel to enable terrestrial mammals to locomote in a natural environment is still relatively obscure. In this review, we first briefly describe what is known about how the two sensory systems control locomotion and use this information to formulate a hypothesis that the weight of the role of segmental feedback is less important at slower speeds but increases at higher speeds, whereas the weight of the role of vestibular system has the opposite relation. The new avenues presented by the latest developments in molecular sciences using the mouse as the model system allow the direct testing of the hypothesis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.