Evidence map›Paper›PMID 33540553›Full record

ArticleInternational journal of molecular sciences2021

Anti-Infective and Anti-Inflammatory Mode of Action of Peptide 19-2.5.

Lena Heinbockel, Günther Weindl, Wilmar Correa, Julius Brandenburg, Norbert Reiling, Karl-Heinz Wiesmüller, Tobias Schürholz, Thomas Gutsmann, Guillermo Martinez de Tejada, Karl Mauss and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Lena HeinbockelBrandenburg Antiinfektiva GmbH, c/o Forschungszentrum Borstel, Leibniz Lungenzentrum, Parkallee 10 b, D-23845 Borstel, Germany.
Günther WeindlPharmakologie und Toxikologie, Pharmazeutisches Institut, Universität Bonn, Gerhard-Domagk-Str. 3, 53121 Bonn, Germany.ORCID 0000-0002-4493-7597
Wilmar CorreaForschungszentrum Borstel, Leibniz Lungenzentrum FG Biophysik, Parkallee 10, D-23845 Borstel, Germany.
Julius BrandenburgForschungszentrum Borstel, Leibniz-Lungenzentrum, FG Molekulare Grenzflächenbiologie, Parkallee 22, D-23845 Borstel, Germany.
Norbert ReilingForschungszentrum Borstel, Leibniz-Lungenzentrum, FG Molekulare Grenzflächenbiologie, Parkallee 22, D-23845 Borstel, Germany.
Karl-Heinz WiesmüllerEMC MIcrocollections, Sindelfinger Straße 3, D-72070 Tübingen, Germany.
Tobias SchürholzKlinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitäsmedizin Rostock, Schillngallee 35, 18057 Rostock, Germany.ORCID 0000-0003-3830-3499
Thomas GutsmannForschungszentrum Borstel, Leibniz Lungenzentrum FG Biophysik, Parkallee 10, D-23845 Borstel, Germany.
Guillermo Martinez de TejadaDepartamento de Microbiologia, Universidad de Navarra, Irunlarrea 1, E-31008 Pamplona, Spain.ORCID 0000-0003-3755-451X
Karl MaussBrandenburg Antiinfektiva GmbH, c/o Forschungszentrum Borstel, Leibniz Lungenzentrum, Parkallee 10 b, D-23845 Borstel, Germany.
Klaus BrandenburgBrandenburg Antiinfektiva GmbH, c/o Forschungszentrum Borstel, Leibniz Lungenzentrum, Parkallee 10 b, D-23845 Borstel, Germany.
Research Center Borstel - Leibniz Lung Center · DEAsklepios Klinik Altona · DEEMC Microcollections (Germany) · DEUniversidad de Navarra · ESUniversitätsmedizin Rostock · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polypeptide Pep19-2.5 (Aspidasept

Indexed as

InflammationAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsDisease Models, AnimalEndotoxemiaHumansLipopolysaccharidesMicePeptidesAnti-Infective AgentsAnti-Inflammatory AgentsLipopolysaccharidesPep19-2.5 peptidePeptidesantimicrobial peptidesAspidaseptinflammationlipopolysaccharidepathogen-associated patternspharmacodynamicssepsis

Identifiers

PMID33540553
PMCPMC7867136
OpenAlexW3127558748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.