ArticleJournal of clinical medicine2021
Impact of 1-Hour Bundle Achievement in Septic Shock.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Construction of a sensitive indicator evaluation system for sepsis care quality: a three-stage mixed-method Delphi study.Frontiers in medicine · 2026Pooled it
- Hour-1 Sepsis Bundle: Updated Evidence.Journal of clinical medicine · 2026Review
- Completion of the 1-Hour Sepsis Bundle on 90-Day Mortality in Adult Patients With Sepsis.Journal of the American College of Emergency Physicians open · 2026Article
- Sepsis Bundle Compliance Before and After the Implementation of a Protocolized Sepsis Program.Cureus · 2025Article
- Extremely early initiation of vasopressors might not decrease short-term mortality for adults with septic shock: a systematic review and meta-analysis.Annals of intensive care · 2025Article
- "We have theoretical knowledge, but these are not things we do regularly": District hospital's healthcare workers' experiences and perceptions on gestational diabetes mellitus screening in Tanzania.PLOS global public health · 2025Article
- Article
- Influence of underlying condition and performance of sepsis bundle in very old patients with sepsis: a nationwide cohort study.Annals of intensive care · 2024Article
- The Effect of a Care Bundle on the Rate of Blood Culture Contamination in a General Intensive Care Unit.Antibiotics (Basel, Switzerland) · 2024Article
- An observational study on the impact of overcrowding towards door-to-antibiotic time among sepsis patients presented to emergency department of a tertiary academic hospital.BMC emergency medicine · 2024Observational
- Prediction of vasopressor requirement among hypotensive patients with suspected infection: usefulness of diastolic shock index and lactate.Clinical and experimental emergency medicine · 2022Article
- Door-to-antibiotic Time and In-hospital Mortality of Elder Patients Presenting to Emergency Department with Sepsis; a Cross-Sectional Study.Archives of academic emergency medicine · 2021Article
Corrections and comments
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Authors and funding
15 authors at 11 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to address the impact of 1-hr bundle achievement on outcomes in septic shock patients. Secondary analysis of multicenter prospectively collected data on septic shock patients who had undergone protocolized resuscitation bundle therapy at emergency departments was conducted. In-hospital mortality according to 1-h bundle achievement was compared using multivariable logistic regression analysis. Patients were also divided into 3 groups according to the time of bundle achievement and outcomes were compared to examine the difference in outcome for each group over time: group 1 (≤1 h reference), group 2 (1-3 h) and group 3 (3-6 h). In total, 1612 patients with septic shock were included. The 1-h bundle was achieved in 461 (28.6%) patients. The group that achieved the 1-h bundle did not show a significant difference in in-hospital mortality compared to the group that did not achieve the 1-h bundle on multivariable logistic regression analysis (<1 vs. >1 h) (odds ratio = 0.74,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.