Evidence map›Paper›PMID 33540511›Full record

ArticleToxins2021

Cytotoxic and Genotoxic Effects of Cyanobacterial and Algal Extracts-Microcystin and Retinoic Acid Content.

Michal Bittner, Alja Štern, Marie Smutná, Klára Hilscherová, Bojana Žegura

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michal BittnerRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Alja ŠternDepartment of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7531-1215
Marie SmutnáRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Klára HilscherováRECETOX, Faculty of Science, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Bojana ŽeguraDepartment of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia.ORCID 0000-0002-5731-0785
Masaryk University · CZNational Institute of Biology · SI

Funding

European Cooperation in Science and Technology STSM-ES1105-24073Grantová Agentura České Republiky 18-15199SJavna Agencija za Raziskovalno Dejavnost RS P1-0245Ministry of Education, Youth and Sports of the Czech Republic LM2011028Ministry of Education, Youth and Sports of the Czech Republic LO1214
6 · The paper itself

Abstract

In the last decade, it has become evident that complex mixtures of cyanobacterial bioactive substances, simultaneously present in blooms, often exert adverse effects that are different from those of pure cyanotoxins, and awareness has been raised on the importance of studying complex mixtures and chemical interactions. We aimed to investigate cytotoxic and genotoxic effects of complex extracts from laboratory cultures of cyanobacterial species from different orders (

Indexed as

DNA DamageAlkaloidsCell SurvivalChlorophytaChromatography, LiquidComet AssayCyanobacteriaCyanobacteria ToxinsHep G2 CellsHumansMicrocystinsMicronuclei, Chromosome-DefectiveMicronucleus TestsSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryTretinoinAlkaloidsCyanobacteria ToxinscylindrospermopsinmicrocystinMicrocystinsTretinoinalgaechemical analysiscomplex mixturescyanobacteriacyanotoxinscytotoxicityextractsgenotoxicitymicrocystinsretinoic acids

Identifiers

PMID33540511
PMCPMC7912913
OpenAlexW3128622068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.