Evidence map›Paper›PMID 33540364›Full record

ArticleSexual medicine2021

Which Happens Earlier, Lower Urinary Tract Symptoms or Erectile Dysfunction?

Yohei Matsuda, Ko Kobayashi, Fumimasa Fukuta, Akio Takayanagi, Kohei Hashimoto, Toshiaki Tanaka, Naoya Masumori

Open access · goldAbstract read
In one paragraph

Article in Sexual medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yohei MatsudaDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Ko KobayashiDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan. Electronic address: kou@sapmed.ac.jp.
Fumimasa FukutaDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Akio TakayanagiDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Kohei HashimotoDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Toshiaki TanakaDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Naoya MasumoriDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough an association between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) has been suggested, it was not clarified whether LUTS developed before ED or vice versa.

aimTo clarify whether LUTS develop before ED or vice versa and which symptoms predicted the onset of the other condition in a longitudinal community-based study.

methodsWe conducted a longitudinal community-based study on LUTS and ED in aged Japanese men. A follow-up study was conducted to determine their longitudinal changes of LUTS and ED after 15 years. Erectile function was evaluated using a validated questionnaire. LUTS were evaluated based on the International Prostate Symptom Score, quality of life index, and prostate volume.

main outcome measureWe evaluated the baseline symptoms among the participants who had LUTS and ED in the follow-up survey and what prior symptoms could predict the onset of the other condition using the data from a long-term longitudinal survey.

resultsA total of 108 men were enrolled in this study. Of the 47 men having both LUTS and ED in the follow-up study, men having only LUTS (n = 16) were more frequent than those having only ED (n = 6) in the initial study. Likewise, of the 38 men having both nocturia and ED at the time of the follow-up study, those having only nocturia (n = 12) were more frequent than those having only ED (n = 5) in the initial study. In multivariable analysis, age 60 years or older (odds ratio: 7.10, 95% CI: 2.09-24.13) and nocturia (odds ratio: 15.83, 95% CI: 3.05-82.15) were independent predictors for the onset of ED.

conclusionThere were more men with prior onset of LUTS, especially nocturia, than men with prior onset of ED among those with both ED and LUTS in this long-term longitudinal study. Nocturia may be a predictor of subsequent ED. Matsuda Y, Kobayashi K, Fukuta F, et al. Which Happens Earlier, Lower Urinary Tract Symptoms or Erectile Dysfunction?. J Sex Med 2021;9:100275.

Indexed as

Benign Prostatic HyperplasiaCommunity-Based StudyLongitudinal StudyNocturiaSexual Dysfunction

Identifiers

PMID33540364
PMCPMC8072163
OpenAlexW3126370440

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.