Evidence map›Paper›PMID 33539779›Full record

ArticleThe American journal of pathology2021

MicroRNA155 Plays a Critical Role in the Pathogenesis of Cutaneous Leishmania major Infection by Promoting a Th2 Response and Attenuating Dendritic Cell Activity.

Sanjay Varikuti, Chaitenya Verma, Gayathri Natarajan, Steve Oghumu, Abhay R Satoskar

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  8. STK11 mutation affects tumor proliferation by impacting CD4Central-European journal of immunology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sanjay VarikutiDepartment of Pathology, The Ohio State University Medical Center, Columbus, Ohio.
Chaitenya VermaDepartment of Pathology, The Ohio State University Medical Center, Columbus, Ohio.
Gayathri NatarajanDepartment of Pathology, The Ohio State University Medical Center, Columbus, Ohio.
Steve OghumuDepartment of Pathology, The Ohio State University Medical Center, Columbus, Ohio.
Abhay R SatoskarDepartment of Pathology, The Ohio State University Medical Center, Columbus, Ohio; Department of Microbiology, The Ohio State University, Columbus, Ohio. Electronic address: abhay.satoskar@osumc.edu.
The Ohio State University Wexner Medical Center · US

Funding

Mechanisms of Oral Cancer Inhibition by Bioactive Phytochemicals in Black RaspberriesK01CA207599 · NCI · OHIO STATE UNIVERSITY · PI OGHUMU, STEVE ONYEKA · 2017 to 2021
$715k
Characterization of bystander immunosuppression during visceral leishmaniasisR21AI138555 · NIAID · OHIO STATE UNIVERSITY · PI SATOSKAR, ABHAY R · 2018 to 2019
$429k
NCI NIH HHS K01 CA207599NIAID NIH HHS R21 AI138555
6 · The paper itself

Abstract

Interferon (IFN)-γ is indispensable in the resolution of cutaneous leishmaniasis (CL), while the Th2 cytokines IL-4, IL-10, and IL-13 mediate susceptibility. A recent study found that miR155, which promotes CD4

Indexed as

AnimalsCD8-Positive T-LymphocytesCytokinesDendritic CellsFemaleKiller Cells, NaturalLeishmania majorLeishmaniasis, CutaneousMiceMice, Inbred C57BLMicroRNAsTh2 CellsCytokinesMicroRNAsMirn155 microRNA, mouse

Identifiers

PMID33539779
PMCPMC8132173
OpenAlexW3127076718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.