ArticleThe Lancet. Respiratory medicine2021
Geography, generalisability, and susceptibility in clinical trials.
Abstract read
In one paragraph
Article in The Lancet. Respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of socioeconomic status on enrollment in clinical trials for cancer: A systematic review.Cancer medicine · 2024Pooled it
- Pooled it
- Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms.Clinical and translational science · 2023Trial
- Implementation of decentralized clinical trials in Korea from a resource-based perspective.Translational and clinical pharmacology · 2026Article
- Serum zinc level independently predicts need for inpatient intubation among patients hospitalized with COVID-19: A prospective observational study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Observational
- Health status, health behavior and perceived stress of nursing staff in Germany: a scoping review.BMC nursing · 2026Article
- Reply to Cheng and Wei: Limitations in the Study of Vitamin D Supplementation and Severe Asthma Exacerbations.American journal of respiratory and critical care medicine · 2025Article
- Factors associated with placebo response rate in randomized controlled trials of antiseizure medications for focal epilepsy.Epilepsia · 2025Article
- Duke Research at Pickett: The evolution of a free-standing research site partnering with communities toward health equity advancement.Journal of clinical and translational science · 2025Article
- Disentangling impacts of multiple pollutants on acute cardiovascular events in New York city: A case-crossover analysis.Environmental research · 2024Article
- Analysis of the distribution of trial sites in South Korea using social network analysis.Translational and clinical pharmacology · 2023Article
- Comparison of Racial, Ethnic, and Geographic Location Diversity of Participants Enrolled in Clinic-Based vs 2 Remote COVID-19 Clinical Trials.JAMA network open · 2022Article
- Real-Life Response to Erenumab in a Therapy-Resistant Case Series of Migraine Patients From the Province of Québec, Eastern Canada.Clinical drug investigation · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
41 authors.
Jane E CloughertyDepartment of Environmental and Occupational Health, Drexel University Dornsife School of Public Health, Philadelphia, PA 19104, USA. Electronic address: jec373@drexel.edu.
Ellen J KinneeUniversity Center for Social and Urban Research, University of Pittsburgh, Pittsburgh, PA, USA.
Juan Carlos CardetDepartment of Internal Medicine, University of South Florida, Tampa, FL, USA.
David MaugerDepartment of Public Health Sciences, Penn State University, Hershey, PA, USA.
Leonard BacharierDepartment of Pediatrics, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Avraham BeigelmanThe Kipper Institute of Allergy and Immunology, Schneider Children's Medical Center of Israel, Tel Aviv University, Tel Aviv, Israel.
Kathryn V BlakeBiomedical Research Department, Nemours Children's Health System, Jacksonville, FL, USA.
Michael D CabanaDepartment of Pediatrics, Children's Hospital at Montefiore and the Albert Einstein College of Medicine, Bronx, NY, USA.
Mario CastroDivision of Pulmonary, Critical Care and Sleep Medicine, University of Kansas School of Medicine, Kansas City, KS, USA.
James F ChmielDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Ronina CovarDepartment of Pediatrics, National Jewish Health, Denver, CO, USA.
Anne FitzpatrickDepartment of Pediatrics, Emory University, Atlanta, GA, USA.
Jonathan M GaffinDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Deborah GentileCommunity Partners in Asthma Care, McMurray, PA, USA.
Elliot IsraelDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard University, Boston MA, USA.
Daniel J JacksonDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Monica KraftDepartment of Medicine, University of Arizona, Tucson, AZ, USA.
Jerry A KrishnanBreathe Chicago Center, University of Illinois at Chicago, Chicago, IL, USA.
Harsha Vardhan KumarDivision of Allergy/Immunology/Pulmonology, University of Illinois at Chicago, Chicago, IL, USA.
Jason E LangDepartment of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Stephen C LazarusDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Robert F LemanskeDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
John LimaPharmacogenomics & Translational Research, Nemours Children's Health System, Jacksonville, FL, USA.
Fernando D MartinezAsthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.
Wayne MorganAsthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.
James MoyDepartment of Medicine, Rush University Medical Center, Chicago, IL, USA.
Ross MyersDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Edward T NaureckasDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Victor E OrtegaDepartment of Internal Medicine, Winston-Salam, NC, USA; Center for Precision Medicine at the Wake Forest School of Medicine, Winston-Salam, NC, USA.
Stephen P PetersDepartment of Internal Medicine, Winston-Salam, NC, USA.
Wanda PhipatanakulDivision of Allergy/Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Jacqueline A PongracicDepartment of Pediatrics, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Kristie RossDepartment of Pediatrics, Case Western Reserve University School of Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
William J SheehanDivision of Allergy/Immunology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Lewis J SmithDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago IL, USA.
Julian SolwayDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Christine A SorknessDivision of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Michael E WechslerDepartment of Medicine, National Jewish Health, Denver, CO, USA.
Sally WenzelDepartment of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA.
Steven R WhiteDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Fernando HolguinDivision of Pulmonary Sciences & Critical Care, University of Colorado, Denver, CO, USA.
Funding
Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)U10HL098115 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2009 to 2015
$57.6MNorthwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8MRADx-UP: Improving the Response of Local Urban and Rural Communities to Disparities in Covid-19 TestingUL1TR002366 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mario Castro, JAMES STEVEN LEEDER · 2017 to 2026
$44.3MSOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7MClinical Centers for the NHLBI Asthma Network (AsthmaNet)U10HL098075 · NHLBI · NATIONAL JEWISH HEALTH · PI SZEFLER, STANLEY J., WECHSLER, MICHAEL E · 2009 to 2015
$5.1MAsthmaNet: UW-Madison Clinical and Translational Research CenterU10HL098090 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SORKNESS, CHRISTINE ANNE · 2009 to 2015
$4.8MUCSF AsthmaNet Clinical CenterU10HL098107 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CABANA, MICHAEL D, LAZARUS, STEPHEN C · 2009 to 2015
$4.8MAsthmaNet: Phenotypic Influences on Asthma TreatmentsU10HL098177 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOLGUIN, FERNANDO, WENZEL, SALLY E · 2009 to 2015
$4.7MArizona/Duke Clinical Center for AsthmaNetU10HL098112 · NHLBI · UNIVERSITY OF ARIZONA · PI KRAFT, MONICA, MARTINEZ, FERNANDO D · 2009 to 2015
$4.7MChicagoland Metropolitan AsthmaNet Consortium (CMAC)U10HL098096 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KRISHNAN, JERRY A., PONGRACIC, JACQUELINE · 2009 to 2015
$4.6MWashington University AsthmaNetU10HL098098 · NHLBI · WASHINGTON UNIVERSITY · PI BACHARIER, LEONARD B, CASTRO, MARIO · 2009 to 2015
$4.5MValidating GIS-based methods to address spatial uncertainty in clinical trialsR01HL114536 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CLOUGHERTY, JANE ELLEN, HOLGUIN, FERNANDO · 2012 to 2016
$1.8MNCATS NIH HHS UL1 TR001422NCATS NIH HHS UL1 TR002366NHLBI NIH HHS R01 HL114536NHLBI NIH HHS U10 HL098075NHLBI NIH HHS U10 HL098090NHLBI NIH HHS U10 HL098096NHLBI NIH HHS U10 HL098098NHLBI NIH HHS U10 HL098107NHLBI NIH HHS U10 HL098112NHLBI NIH HHS U10 HL098115NHLBI NIH HHS U10 HL098177NIAID NIH HHS K23 AI125785NIEHS NIH HHS P30 ES006694
Abstract
PubMed holds no abstract for this paper.
Indexed as
Patient SelectionReproducibility of ResultsSocial ClassGeographyHumansMinority GroupsRandomized Controlled Trials as Topic
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.