Evidence map›Paper›PMID 33539602›Full record

ArticleAnimal genetics2021

Roan, ticked and clear coat patterns in the canine are associated with three haplotypes near usherin on CFA38.

L Brancalion, B Haase, H Mazrier, C E Willet, K Lindblad-Toh, F Lingaas, C M Wade

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L BrancalionFaculty of Science, University of Sydney, Camperdown, 2006, NSW, Australia.
B HaaseFaculty of Science, University of Sydney, Camperdown, 2006, NSW, Australia.
H MazrierFaculty of Science, University of Sydney, Camperdown, 2006, NSW, Australia.
C E WilletSydney Informatics Hub, University of Sydney, Camperdown, 2006, NSW, Australia.
K Lindblad-TohThe Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.
F LingaasSection of Medical Genetics, Department of Preclinical Sciences and Pathology, Norwegian University of Life Sciences, Oslo, N-0102, Norway.
C M WadeFaculty of Science, University of Sydney, Camperdown, 2006, NSW, Australia.ORCID https://orcid.org/0000-0003-3413-4771

Funding

American Kennel Club Canine Health Foundation 02157-397 MOU
6 · The paper itself

Abstract

White coat patterning is a feature of many dog breeds and is known to be coded primarily by the gene micropthalmia-associated transcription factor (MITF). This patterning in the coat can be modified by other factors to produce the attractive phenotypes termed 'ticked' and 'roan' that describe the presence of flecks of color that vary in distribution and intensity within otherwise 'clear' white markings. The appearance of the pigment in the white patterning caused by ticking and roaning intensifies in the weeks after birth. We applied genome-wide association to compare English Cocker Spaniels of roan phenotype (N = 34) with parti-color (non-roan) English Cocker Spaniels (N = 9) and identified an associated locus on CFA 38, CFA38:11 057 040 (P

Indexed as

AllelesAnimalsDogsFemaleGenetic Association StudiesGenotypeHair ColorHaplotypesMalePhenotypecoat-colorpigmentationUSH2Ausherin

Identifiers

PMID33539602
PMCPMC7986734

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.