Evidence map›Paper›PMID 33539475›Full record

ArticlePloS one2021

Cumulative incidence of midline incisional hernia and its surgical treatment after radical cystectomy and urinary diversion for bladder cancer: A nation-wide population-based study.

Fredrik Liedberg, Oskar Hagberg, Firas Aljabery, Truls Gårdmark, Staffan Jahnson, Tomas Jerlström, Agneta Montgomery, Amir Sherif, Viveka Ströck, Christel Häggström and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Fredrik LiedbergDepartment of Urology Skåne University Hospital, Malmö, Sweden.ORCID 0000-0001-8193-0370
Oskar HagbergInstitution of Translational Medicine, Lund University, Malmö, Sweden.
Firas AljaberyDivision of Urology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Truls GårdmarkDepartment of Clinical Sciences, Danderyd Hospital, Karolinska Institute, Stockholm, Sweden.
Staffan JahnsonDivision of Urology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Tomas JerlströmDepartment of Urology, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID 0000-0003-4615-5238
Agneta MontgomeryInstitution of Clinical Sciences Malmö, Surgical Research Unit, Lund University, Lund, Sweden.
Amir SherifDepartment of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden.ORCID 0000-0002-3675-3050
Viveka StröckDepartment of Urology, Sahlgrenska University Hospital and Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Christel HäggströmDepartment of Biobank Research, Umeå University, Umeå, Sweden.
Lars HolmbergDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Lund University · SELinköping University · SEUppsala University · SEKarolinska Institutet · SEÖrebro University · SESahlgrenska University Hospital · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo study the cumulative incidence and surgical treatment of midline incisional hernia (MIH) after cystectomy for bladder cancer.

methodsIn the nationwide Bladder Cancer Data Base Sweden (BladderBaSe), cystectomy was performed in 5646 individuals. Cumulative incidence MIH and surgery for MIH were investigated in relation to age, gender, comorbidity, previous laparotomy and/or inguinal hernia repair, operative technique, primary/secondary cystectomy, postoperative wound dehiscence, year of surgery, and period-specific mean annual hospital cystectomy volume (PSMAV).

resultsThree years after cystectomy the cumulative incidence of MIH and surgery for MIH was 8% and 4%, respectively. The cumulative incidence MIH was 12%, 9% and 7% in patients having urinary diversion with continent cutaneous pouch, orthotopic neobladder and ileal conduit. Patients with postoperative wound dehiscence had a higher three-year cumulative incidence MIH (20%) compared to 8% without. The corresponding cumulative incidence surgery for MIH three years after cystectomy was 9%, 6%, and 4% for continent cutaneous, neobladder, and conduit diversion, respectively, and 11% for individuals with postoperative wound dehiscence (vs 4% without). Using multivariable Cox regression, secondary cystectomy (HR 1.3 (1.0-1.7)), continent cutaneous diversion (HR 1.9 (1.1-2.4)), robot-assisted cystectomy (HR 1.8 (1-3.2)), wound dehiscence (HR 3.0 (2.0-4.7)), cystectomy in hospitals with PSMAV 10-25 (HR 1.4 (1.0-1.9)), as well as cystectomy during later years (HRs 2.5-3.1) were all independently associated with increased risk of MIH.

conclusionsThe cumulative incidence of MIH was 8% three years postoperatively, and increase over time. Avoiding postoperative wound dehiscence after midline closure is important to decrease the risk of MIH.

Indexed as

AgedCarcinoma, Transitional CellCystectomyDatabases, FactualFemaleHumansIncidenceIncisional HerniaMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSwedenUrinary BladderUrinary Bladder NeoplasmsUrinary Diversion

Identifiers

PMID33539475
PMCPMC7861544
OpenAlexW3127617832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.