Evidence map›Paper›PMID 33539455›Full record

ArticlePloS one2021

Prevalence and associated factors of impaired renal function and albuminuria among adult patients admitted to a hospital in Northeast Ethiopia.

Temesgen Fiseha, Ermiyas Ahmed, Semagn Chalie, Angesom Gebreweld

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Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

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10citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Temesgen FisehaDepartment of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-9079-7030
Ermiyas AhmedDepartment of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Semagn ChalieDepartment of Clinical Laboratory Science, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Angesom GebreweldDepartment of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is increasingly common in hospitalized patients and is associated with increased risk for in-hospital morbidity and mortality. However, data regarding the prevalence of CKD in the African hospitalized patient population are limited. We therefore examined the prevalence and associated factors of impaired renal function and albuminuria among adult patients admitted to the internal medicine wards of a hospital in Northeast Ethiopia.

methodsA cross-sectional study was conducted from January 1 to April 30, 2020 at the inpatient settings of Dessie referral hospital. Data on demographics and medical history were obtained, and serum creatinine and albuminuria were analyzed. Estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease (MDRD) equation. CKD was defined as impaired eGFR (<60 ml/min/1.73m2) and/or albuminuria. Univariate and multivariable analysis were conducted to determine factors associated with impaired eGFR and albuminuria.

resultsA total of 369 patients were included in this study. The prevalence of impaired eGFR was 19.0% (95%CI: 15.2%-23.2%) and albuminuria was 30.9% (95%CI: 26.3%-35.7%). Overall, 33.9% (95%CI: 29.2%-38.9%) of the patients had some degree of CKD, but only 21.6% (95%CI: 15.1%-29.4%) were aware of their renal disease. In multivariable analysis, older age, a family history of kidney disease, diabetes, hypertension and HIV were independently associated with both impaired eGFR and albuminuria while male gender was independently associated with only albuminuria.

conclusionsCKD is common in adult patients admitted to the internal medicine wards, but only few patients are aware of their condition. These findings highlight the need for feasible approaches to timely identify kidney disease and raise awareness on the importance of detection and early intervention in the inpatient settings.

Indexed as

AlbuminuriaCross-Sectional StudiesEthiopiaGlomerular Filtration RateHospitalsHumansPrevalenceRenal Insufficiency, ChronicRisk Factors

Identifiers

PMID33539455
PMCPMC7861367

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