Evidence map›Paper›PMID 33539118›Full record

ArticleJournal of abnormal psychology2021

Neuroticism and reward-related ventral striatum activity: Probing vulnerability to stress-related depression.

Erin Bondy, David A A Baranger, Jared Balbona, Kendall Sputo, Sarah E Paul, Thomas F Oltmanns, Ryan Bogdan

Open access · hybridAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  9. Anhedonia in Anxiety Disorders.Current topics in behavioral neurosciences · 2022
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  12. Article
  13. Tutorial: Power analyses for interaction effects in cross-sectional regressions.Advances in methods and practices in psychological science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Erin BondyDepartment of Psychological and Brain Sciences.ORCID 0000-0002-1839-2378
David A A BarangerDepartment of Psychiatry.ORCID 0000-0002-6659-357X
Jared BalbonaInstitute for Behavioral Genetics.ORCID 0000-0003-4466-248X
Kendall SputoDepartment of Psychological and Brain Sciences.ORCID 0000-0002-3327-9912
Sarah E PaulDepartment of Psychological and Brain Sciences.ORCID 0000-0003-0320-7907
Thomas F OltmannsDepartment of Psychological and Brain Sciences.
Ryan BogdanDepartment of Psychological and Brain Sciences.ORCID 0000-0002-1430-1045
Institute for Behavioral Medicine · US

Funding

MAPPING THE HUMAN CONNECTOME DURING TYPICAL AGINGU01AG052564 · NIA · WASHINGTON UNIVERSITY · PI SALAT, DAVID H, TERPSTRA, MELISSA J · 2016 to 2020
$18.9M
Systems and Molecular Neurobiology Training ProgramT32GM008151 · NIGMS · WASHINGTON UNIVERSITY · PI SNYDER, LAWRENCE H · 1985 to 2019
$6.5M
Intergenerational Transmission of Stress: Psychosocial and Biological MechanismsR01AG061162 · NIA · WASHINGTON UNIVERSITY · PI BOGDAN, RYAN H · 2019 to 2023
$3.1M
GENETICS, THE ADOLESCENT BRAIN, AND ADDICTION LIABILITY: A LONGITUDINAL TWIN STUDYR01HD083614 · NICHD · WASHINGTON UNIVERSITY · PI ANOKHIN, ANDREY P. · 2016 to 2020
$3.0M
Personality and Health in Later Life: Psychosocial and Biological MechanismsR01AG045231 · NIA · WASHINGTON UNIVERSITY · PI OLTMANNS, THOMAS · 2014 to 2018
$2.9M
Neurogenetic Pathways to Drug Use in Young AdultsR01DA033369 · NIDA · DUKE UNIVERSITY · PI HARIRI, AHMAD R. · 2013 to 2016
$1.4M
Age-Related Changes in Language ProcessingR56AG059265 · NIA · WASHINGTON UNIVERSITY · PI PEELLE, JONATHAN E · 2019 to 2019
$479k
Modeling poly-genomic risk in the relationship between brain structure and alcohol involvement from adolescence through adulthoodR21AA027827 · NIAAA · WASHINGTON UNIVERSITY · PI BOGDAN, RYAN H · 2019 to 2020
$413k
Inflammation and Reward-related Behavioral and Neural PhenotypesF31MH123105 · NIMH · WASHINGTON UNIVERSITY · PI BONDY, ERIN · 2020 to 2022
$92k
National Science FoundationNIAAA NIH HHS R21 AA027827NIA NIH HHS R01 AG045231NIA NIH HHS R01 AG061162NIA NIH HHS R56 AG059265NIA NIH HHS U01 AG052564NICHD NIH HHS R01 HD083614NIDA NIH HHS R01 DA033369NIGMS NIH HHS T32 GM008151NIH HHSNIMH NIH HHS F31 MH123105Washington University in St. Louis; McDonnell Center for Systems Neuroscience
6 · The paper itself

Abstract

Elevated neuroticism may confer vulnerability to the depressogenic effects of stressful life events (SLEs). However, the mechanisms underlying this susceptibility remain poorly understood. Accumulating evidence suggests that stress-related disruptions in neural reward processing might undergird links between stress and depression. Using data from the Saint Louis Personality and Aging Network (SPAN) study and Duke Neurogenetics Study (DNS), we examined whether neuroticism moderates links between stressful life events (SLE) and depression as well as SLEs and ventral striatum (VS) response to reward. In the longitudinal SPAN sample (

Indexed as

RewardAdolescentAdultAgedAge FactorsCross-Sectional StudiesDepressive DisorderEvoked PotentialsFemaleHumansLongitudinal StudiesMaleMiddle AgedNeuroticismStress, PsychologicalVentral Striatum

Identifiers

PMID33539118
PMCPMC8110089
OpenAlexW3127508858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.