Evidence map›Paper›PMID 33538988›Full record

ArticleJournal of thrombosis and thrombolysis2021

Calf vein thrombosis outcomes comparing patients with and without cancer.

Ahmed K Pasha, Wiktoria Kuczmik, Waldemar E Wysokinski, Ana I Casanegra, Damon Houghton, Danielle T Vlazny, Abigail Mertzig, Yumiko Hirao-Try, Launia White, David Hodge and 1 more

Abstract read
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In one paragraph

Article in Journal of thrombosis and thrombolysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ahmed K PashaGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Wiktoria KuczmikGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Waldemar E WysokinskiGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Ana I CasanegraGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Damon HoughtonGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Danielle T VlaznyGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Abigail MertzigGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Yumiko Hirao-TryGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Launia WhiteDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.
David HodgeDepartment of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.
Robert McBane IiGonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. mcbane.robert@mayo.edu.ORCID http://orcid.org/0000-0001-8727-8029
Mayo Clinic · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distal or calf deep vein thrombosis (DVT) are said to have low rates of propagation, embolization, and recurrence. The objective of this study was to determine outcomes among cancer patients with calf DVT compared to those without cancer. Consecutive patients with ultrasound confirmed acute calf DVT (3/1/2013-8/10/2019) were assessed for venous thromboembolism (VTE) recurrence and bleeding outcomes compared by cancer status. There were 830 patients with isolated calf DVT; 243 with cancer and 587 without cancer. Cancer patients were older (65.9 ± 11.4 vs. 62.0 ± 15.9 years; p = 0.006), with less frequent recent hospitalization (31.7% vs. 48.0%; p < 0.001), surgery (30.0% vs. 38.0%; p = 0.03), or trauma (3.7% vs. 19.9%; p < 0.001). The four most common cancers included hematologic malignancies (20.6%), lung (11.5%), gastrointestinal (10.3%), and ovarian/GYN (9.1%). Nearly half of patients had metastatic disease (43.8%) and 57% were receiving chemotherapy. VTE recurrence rates were similar for patients with (7.1%) and without cancer (4.0%; p = 0.105). Major bleeding (6.3% vs. 2.3%; p = 0.007) were greater for cancer patients while clinical relevant non major bleeding rates did not differ (7.1% vs. 4.6%; p = 0.159). In this retrospective analysis, cancer patients with calf DVT have similar rates of VTE recurrence but higher major bleeding outcomes compared to patients without cancer.

Indexed as

Mesenteric IschemiaVenous ThromboembolismVenous ThrombosisAnticoagulantsHemorrhageHumansNeoplasm Recurrence, LocalRecurrenceRetrospective StudiesRisk FactorsAnticoagulantsCalf deep vein thrombosisCancerDistal deep vein thrombosisMajor bleedingVenous thromboembolism

Identifiers

PMID33538988
OpenAlexW3126413403

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.