Evidence map›Paper›PMID 33538309›Full record

ReviewTranslational behavioral medicine2021

Synthesizing the literature on physical activity among children and adolescents affected by cancer: evidence for the international Pediatric Oncology Exercise Guidelines (iPOEG).

Amanda Wurz, Emma McLaughlin, Conné Lategan, Kelsey Ellis, S Nicole Culos-Reed

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Translational behavioral medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07488494 (Effective Implementation of the Physical Activity and Motor Skills Intervention for 3-6-year-old Children With Cancer), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07488494 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effective Implementation of the Physical Activity and Motor Skills Intervention for 3-6-year-old Children With Cancer (EMPOWER)

TypeinterventionalSponsorTurku University HospitalRan2026 to 2028Enrolled40ConditionsPhysical Activity During Cancer TreatmentArmsDigital tool for physical activity guidance and follow-up, Physical activity guidance
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness of home-based exercise programs in children with acute lymphoblastic leukemia: A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Implementing health promotion interventions in a pediatric oncology setting: A qualitative study among families impacted by cancer and healthcare professionals.Journal of child health care : for professionals working with children in the hospital and community · 2026
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amanda WurzFaculty of Kinesiology, University of Calgary, Calgary, Canada.
Emma McLaughlinFaculty of Kinesiology, University of Calgary, Calgary, Canada.
Conné LateganFaculty of Kinesiology, University of Calgary, Calgary, Canada.
Kelsey EllisFaculty of Kinesiology, University of Calgary, Calgary, Canada.
S Nicole Culos-ReedFaculty of Kinesiology, University of Calgary, Calgary, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA), including exercise, is safe and beneficial for children and adolescents affected by cancer. Yet, no efforts have been made to collate the breadth of review and experimental articles exploring the effects of PA in this cohort. Thus, a scoping review of review and experimental articles reporting on the effects of PA for children and adolescents affected by cancer was undertaken. Review and experimental articles published in English, summarizing or reporting on the effects of PA interventions for children and adolescents affected by cancer were included. Articles were identified through prior literature, systematic searching, reference list scanning, stakeholder engagement, and a database update. Data were extracted, collated, assessed for quality (reviews) or risk of bias (experimental articles), and summarized narratively. A total of 1,380 articles were identified; 20 review and 69 experimental articles were included. Articles explored PA behavior, physical, psychosocial, cognitive, and "other" outcomes. Improvements, no change, or mixed results were reported across the majority of outcomes explored. Two PA-related adverse events (e.g., a treatable injury, fatigue) were described. Included articles varied greatly in quality and risk of bias. Findings confirm that PA for children and adolescents affected by cancer is a rapidly growing field. More adequately powered research, focused on priority outcomes, adopting appropriate study designs, and adhering to reporting standards is required. Addressing these gaps will enable a better understanding of the effects of PA. Nevertheless, the literature confirms moving more is beneficial and safe for children and adolescents affected by cancer.

Indexed as

Practice Guidelines as TopicAdolescentChildExerciseHumansNeoplasmsPatient SafetyAdolescent cancerChildhood cancerExerciseNarrative reviewPhysical activity

Identifiers

PMID33538309
PMCPMC8033595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.