Evidence map›Paper›PMID 33537950›Full record

ArticleOphthalmology and therapy2021

Lesion-Mapping Software for the Measurement of Subperiosteal Abscess Volume for Pediatric Orbital Cellulitis: A Retrospective Chart Review.

Tejus Pradeep, Gagan Kalra, Joseph K Leader, Jennifer McCoy, Ronak Dixit, Joseph Dohar, Allison Tobey, José-Alain Sahel, Jiantao Pu, Roxana Fu

Open access · goldAbstract read
In one paragraph

Article in Ophthalmology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Tejus PradeepSchool of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Gagan KalraGovernment Medical College and Hospital, Chandigarh, India.
Joseph K LeaderDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Jennifer McCoyUPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Ronak DixitDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Joseph DoharDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Allison TobeyDepartment of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
José-Alain SahelDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Jiantao PuDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. puj@upmc.edu.
Roxana FuDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, 15213, USA. fur3@upmc.edu.
University of Pittsburgh · USChildren's Hospital of Pittsburgh · USGovernment Medical College and Hospital · INJohns Hopkins University · US

Funding

Macro-vasculature: A Novel Image Biomarker of Lung CancerR01CA237277 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PU, JIANTAO · 2020 to 2024
$2.8M
NCI NIH HHS R01 CA237277
6 · The paper itself

Abstract

introductionOur objective was to assess the utility of using lesion-mapping software to calculate precise orbital volumes to predict patients who would benefit from early surgical intervention.

methodsWe retrospectively reviewed patients diagnosed with subperiosteal orbital abscess (SPOA) secondary to sinusitis at a tertiary pediatric hospital from 2005 to 2016. Diagnoses were confirmed by CT scans. Lesion-mapping software was used to measure SPOA volume using initial CT images. Data collected included patient demographics, length of hospital stay, and subsequent medical or surgical treatment.

resultsThirty-three (52%) patients ultimately underwent surgical intervention, while 30 (48%) were managed medically. Between the surgical and medical groups, there were no differences in gender, age, or comorbidities. The surgical group had larger abscess volumes than the medically managed group (0.94 mL vs. 0.31 mL, p < 0.01). Overall, increased SPOA volume was associated with increased age (Pearson's coefficient = 0.374, p ≤ 0.01) and increased total days of intravenous (IV) antibiotic administration (Pearson's coefficient = 0.260, p = 0.039). Patients who underwent surgery on the day of admission had 25% shorter hospital stay than patients who had delayed surgery (p < 0.01). Our calculated sensitivity-optimized SPOA volume cutoff of 0.231 mL yielded sensitivity of 90.9% and specificity of 70.0%.

conclusionsThis is the first study to use lesion-mapping software for precise calculation of SPOA volumes, which can help refine indications for early surgical intervention and help decrease length of hospital stay.

Indexed as

3D volume renderingComputed tomography (CT)Orbital cellulitisSubperiosteal orbital abscess

Identifiers

PMID33537950
PMCPMC8079525
OpenAlexW3128704703

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.