Evidence map›Paper›PMID 33537947›Full record

Observational studyAmerican journal of cardiovascular drugs : drugs, devices, and other interventions2021

Long-Term Antithrombotic Therapy and Clinical Outcomes in Patients with Acute Coronary Syndrome and Renal Impairment: Insights from EPICOR and EPICOR Asia.

Yong Huo, Frans Van de Werf, Yaling Han, Xavier Rossello, Stuart J Pocock, Chee Tang Chin, Stephen W-L Lee, Yi Li, Jie Jiang, Ana Maria Vega and 2 more

2 registry-linked trialsOpen access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in American journal of cardiovascular drugs : drugs, devices, and other interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01171404 completednot on this map

Long-term Follow-up of Antithrombotic Management Patterns in Acute Coronary Syndrome Patients

TypeobservationalSponsorAstraZenecaRan2010 to 2013Enrolled10,568ConditionsACS, Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina
NCT01361386 completednot on this map

Long-Term Follow-up of Antithrombotic Management Patterns in Acute Coronary Syndrome Patients in Asia

TypeobservationalSponsorAstraZenecaRan2011 to 2014Enrolled13,011ConditionsAcute Coronary Syndrome
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. P2yFrontiers in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 5 countries.

Yong HuoDepartment of Cardiology, Peking University First Hospital, 8 Xishiku St., Xicheng District, Beijing, 100034, China. huoyong@263.net.cn.ORCID http://orcid.org/0000-0002-5407-8773
Frans Van de WerfDepartment of Cardiovascular Sciences, KU, Leuven, Belgium.
Yaling HanGeneral Hospital of Shenyang Military Region, Shenyang, China.
Xavier RosselloHealth Research Institute of the Balearic Islands (IdISBa), University Hospital Son Espases, Palma, Spain.
Stuart J PocockDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Chee Tang ChinNational Heart Centre Singapore, Singapore, Singapore.
Stephen W-L LeeQueen Mary Hospital, Hong Kong SAR, China.
Yi LiDepartment of Cardiology, Shenyang Northern Hospital, Shenyang, China.
Jie JiangDepartment of Cardiology, Peking University First Hospital, 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Ana Maria VegaMedical Department, AstraZeneca, Madrid, Spain.
Jesús MedinaMedical Department, AstraZeneca, Madrid, Spain.
Héctor BuenoCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.
AstraZeneca (Spain) · ESGeneral Hospital of Shenyang Military Region · CNPeking University · CNKU Leuven · BELondon School of Hygiene & Tropical Medicine · GBNational Heart Centre Singapore · SGQueen Mary Hospital · CNSpanish National Centre for Cardiovascular Research · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInformation is lacking on long-term management of patients with acute coronary syndrome (ACS) and chronic kidney disease (CKD) (estimated glomerular filtration rate [eGFR] < 60 mL/min/1.73 m

objectivesOur objectives were to describe antithrombotic management patterns and outcomes in patients with ACS with varying renal function from the EPICOR (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients; NCT01171404) and EPICOR Asia (NCT01361386) studies.

methodsEPICOR and EPICOR Asia were prospective observational studies of patients who survived hospitalization for ACS and were enrolled at discharge in 28 countries across Europe, Latin America, and Asia. The studies were conducted from 2010 to 2013 and from 2011 to 2014, respectively. This analysis evaluated patient characteristics and oral antithrombotic management patterns and outcomes up to 2 years post-discharge according to admission eGFR: ≥ 90, 60-89, 30-59, or < 30 mL/min/1.73 m

resultsAmong 22,380 patients with available data, eGFR < 60 mL/min/1.73 m

conclusionsThe presence of CKD in patients with ACS was associated with less aggressive cardiovascular management and an increased risk of cardiovascular events.

Indexed as

Acute Coronary SyndromeAgedAged, 80 and overAge FactorsCardiovascular DiseasesFemaleFibrinolytic AgentsGlomerular Filtration RateHemorrhageHumansMaleMiddle AgedProspective StudiesRenal Insufficiency, ChronicRisk AssessmentRisk FactorsFibrinolytic Agents

Identifiers

PMID33537947
PMCPMC8263456
OpenAlexW3127303964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.