Evidence map›Paper›PMID 33537897›Full record

ArticleMikrochimica acta2021

Polyaniline@Au organic-inorganic nanohybrids with thermometer readout for photothermal immunoassay of tumor marker.

Bing Zhang, Xing Hu, Yejing Jia, Jing Li, Zhihuan Zhao

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. A peroxidase-like magneto-gold nanozyme AuNC@FeFrontiers in bioengineering and biotechnology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bing ZhangCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China. zhangbing01@tyut.edu.cn.ORCID 0000-0003-4363-919X
Xing HuCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Yejing JiaCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Jing LiCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Zhihuan ZhaoCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Taiyuan University of Technology · CNTaiyuan University of Science and Technology · CN

Funding

National Natural Science Foundation of China 21605111
6 · The paper itself

Abstract

A photothermal immunoassay using a thermometer as readout based on polyaniline@Au organic-inorganic nanohybrids was built. Temperature output is acquired due to the photothermal effect of the photothermal nanomaterial. Polyaniline@Au organic-inorganic nanohybrids were synthesized by interfacial reactions with high photothermal conversion efficiency. A sandwich structure of the immunocomplex was prepared on a microplate for determination of carcinoembryonic antigen (CEA) by polyaniline@Au organic-inorganic nanohybrids as nanolabel. The released heat based on light-to-heat conversion from the photothermal nanolabel under NIR irradiation is detectable using the thermometer. The increased temperature is directly proportional to CEA concentration. The linear range of the photothermal immunoassay is 0.20 to 25 ng mL

Indexed as

ThermometersAniline CompoundsAnimalsAntibodies, MonoclonalBiomarkers, TumorCarcinoembryonic AntigenGoldHumansImmunoassayInfrared RaysLimit of DetectionNanocompositesRabbitsReproducibility of ResultsTemperatureAniline CompoundsAntibodies, MonoclonalBiomarkers, TumorCarcinoembryonic AntigenGoldpolyanilineCarcinoembryonic antigenImmunocomplexPhotothermal conversionThermometric detection

Identifiers

PMID33537897
OpenAlexW3127661228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.