Evidence map›Paper›PMID 33537817›Full record

ArticleInternational journal of molecular medicine2021

Bromamine T, a stable active bromine compound, prevents the LPS‑induced inflammatory response.

Stella Baliou, Michael Sofopoulos, Maria Goulielmaki, Demetrios A Spandidos, Petros Ioannou, Anthony M Kyriakopoulos, Vassilios Zoumpourlis

Open access · hybridAbstract read
In one paragraph

Article in International journal of molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Stella BaliouNational Hellenic Research Foundation, 11635 Athens, Greece.
Michael SofopoulosDepartment of Surgical Pathology, Saint Savvas Anticancer Hospital of Athens, 11522 Athens, Greece.
Maria GoulielmakiNational Hellenic Research Foundation, 11635 Athens, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
Petros IoannouDepartment of Internal Medicine and Infectious Diseases, University Hospital of Heraklion, 71110 Heraklion, Greece.
Anthony M KyriakopoulosNasco AD Biotechnology Laboratory, 18536 Pireus, Greece.
Vassilios ZoumpourlisNational Hellenic Research Foundation, 11635 Athens, Greece.
National Hellenic Research Foundation · GRSt Savas Hospital · GRUniversity Hospital of Heraklion · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is the most common cause of most acute and chronic debilitating diseases. Towards unveiling novel therapeutic options for patients with such complications, N‑bromotaurine (TauNHBr) has emerged as a potential anti‑inflammatory agent; however, its therapeutic efficacy is hindered due to its relatively poor stability. To address this challenge, the present study focused on examining the effects of a stable active bromine compound, named bromamine T (BAT). The present study examined the protective properties of BAT against lipopolysaccharide (LPS)‑mediated inflammation

Indexed as

AnimalsAnti-Inflammatory AgentsBromineCell LineCell NucleusDisease Models, AnimalGene Expression RegulationInflammationInflammation MediatorsLipopolysaccharidesMiceMice, Inbred C57BLPhosphorylationProtein TransportRNA, MessengerSulfonamidesAnti-Inflammatory Agentsbromamine TBromineInflammation MediatorsLipopolysaccharidesRNA, MessengerSulfonamidesTaurineTranscription Factor RelAair‑pouch model of inflammationbromamine Tpro‑inflammatory cytokinestaurine

Identifiers

PMID33537817
PMCPMC7891821
OpenAlexW3127616268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.