Evidence map›Paper›PMID 33537680›Full record

ArticleSTAR protocols2021

Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture.

Yu-Ting L Dingle, Mattia Bonzanni, Volha Liaudanskaya, Thomas J F Nieland, David L Kaplan

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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  12. A Review on Bioinks and their Application in Plant Bioprinting.International journal of bioprinting · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yu-Ting L DingleDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Mattia BonzanniDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Volha LiaudanskayaDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Thomas J F NielandDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Tufts University · US

Funding

Tissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6M
Functional three dimensional brain-like tissues to study mechanisms of traumatic brain injuryR01NS092847 · NINDS · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2015 to 2019
$1.8M
Acquisition of Leica confocal/multiphoton microscopeS10OD021624 · OD · TUFTS UNIVERSITY MEDFORD · PI GEORGAKOUDI, IRENE · 2016 to 2016
$600k
NIBIB NIH HHS P41 EB027062NIH HHS S10 OD021624NINDS NIH HHS R01 NS092847
6 · The paper itself

Abstract

Bioengineered 3D tunable neuronal constructs are a versatile platform for studying neuronal network functions, offering numerous advantages over existing technologies and providing for the discovery of new biological insights. Functional neural networks can be evaluated using calcium imaging and quantitatively described using network science. This protocol includes instructions for fabricating protein-based composite scaffolds, 3D

Indexed as

Neural Networks, ComputerAnimalsCell Culture TechniquesCell DifferentiationCerebral CortexCollagenMiceNerve NetNeuronsSilkTissue ScaffoldsCollagenSilkCell cultureMicroscopyNeuroscienceTissue engineering

Identifiers

PMID33537680
PMCPMC7841403
OpenAlexW3122254866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.