ArticleResearch and practice in thrombosis and haemostasis2021
Venous thromboembolism after lower extremity orthopedic surgery: A population-based nationwide cohort study.
Article in Research and practice in thrombosis and haemostasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Pooled it
- Mini-mint ice cubes for early postoperative thirst relief in orthopedic patients undergoing general anesthesia: a randomized controlled trial.Scientific reports · 2026Trial
- Does Staff Education Increase Sequential Compression Device Utilization: A Retrospective Study.HCA healthcare journal of medicine · 2026Article
- Rethinking venous thromboembolism risk after major orthopedic surgery: a transient threat or a persistent problem?Research and practice in thrombosis and haemostasis · 2025Article
- Long-term risk of venous thromboembolism following hip or knee replacement surgery: a population-based matched cohort study.Research and practice in thrombosis and haemostasis · 2025Article
- Post-operative Venous Thromboembolism Prophylaxis for Non-arthroplasty Knee Surgery: A Closed Loop Clinical Audit.Cureus · 2025Article
- Novel horizons in anticoagulation: the emerging role of factor XI inhibitors across different settings.Haematologica · 2024Review
- Risk factors for venous thromboembolism after primary total joint arthroplasty: An analysis of 7511 Taiwanese patients.Journal of the Chinese Medical Association : JCMA · 2024Article
- Therapy adherence, safety and efficacy of rivaroxaban in prevention of venous thromboembolism in patients with hip or knee endoprosthesis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Perioperative Risk Assessment of Patients Using the MyRISK Digital Score Completed Before the Preanesthetic Consultation: Prospective Observational Study.JMIR perioperative medicine · 2023Article
- Venous Thromboembolism Chemoprophylaxis in Knee Arthroscopy: A Break-Even Analysis of Cost.The American journal of sports medicine · 2022Article
- Comparison of the Efficacy and Safety of Rivaroxaban and Enoxaparin as Thromboprophylaxis Agents for Orthopedic Surgery-Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Multimodal Thromboprophylaxis in Patients With a History of Venous Thromboembolism Undergoing Primary and Revision Knee Arthroplasty.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2022Article
- Validation of Postsurgical Venous Thromboembolism Diagnoses of Patients Undergoing Lower Limb Orthopedic Surgery in the Danish National Patient Registry.Clinical epidemiology · 2022Article
- Venous thromboembolism after lower extremity orthopedic surgery: A population-based nationwide cohort study.Research and practice in thrombosis and haemostasis · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVenous thromboembolism (VTE) causes morbidity and mortality in the general population. Several events occur after lower limb orthopedic surgery, but the contribution from various types of lower limb surgery is not well known.
objectiveTo investigate the postoperative incidence of VTE for all types of lower extremity orthopedic surgery compared with the background population.
methodsIndividual-level linkage of Danish nationwide register data for all Danish residents with first-time orthopedic surgery of the lower limb (1996-2017) and, for each of these, four controls from the general population matched on age, sex, and history of VTE. Adjusted hazard ratios (HR) compared the postoperative risk of VTE to the matched controls.
resultsIn total 7203 of the 1 012 823 patients with a first orthopedic procedure had a VTE within 180 days after surgery, corresponding to a postoperative cumulative incidence of 0.71% (95% confidence interval [CI], 0.70-0.73). The cumulative incidence of VTE among controls was 0.11% (95% CI, 0.11-0.12). The HR of VTE within the first 30 days after surgery below knee level was 20.5 (95% CI, 17.9-23.5) compared with matched controls. The HRs of VTE after minor distal procedures (eg, meniscectomy and arthroscopies) were 2.9 (95% CI, 1.9-4.4) to 7.1 (95% CI, 6.4-8.0).
conclusionAll types of lower limb orthopedic surgery including minor distal procedures were associated with higher rates of VTE compared with matched controls, in particular within the first 30 days after surgery.
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