Evidence map›Paper›PMID 33537484›Full record

ArticleHeliyon2021

The use of complex formation manner for spectrophotometric analysis of gatifloxacin drug based on Co(II), Ni(II) and La(III) ions.

Mona M Mostafa, Zeinab H Abd El-Wahab, Aida A Salman, W M Abdelbaset

Abstract read
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Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mona M MostafaNational Organization for Drug Control & Research (NODCAR), Agouza, Dokki, Cairo, Egypt.
Zeinab H Abd El-WahabChemistry Department, Faculty of Science (Girl's), Al-Azhar University, Youssif Abbas St., Nasr-City, P.O. Box 11754, Cairo, Egypt.
Aida A SalmanChemistry Department, Faculty of Science (Girl's), Al-Azhar University, Youssif Abbas St., Nasr-City, P.O. Box 11754, Cairo, Egypt.
W M AbdelbasetNational Organization for Drug Control & Research (NODCAR), Agouza, Dokki, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, a simple and accurate spectrophotometric method was developed to detect gatifloxacin (HGAT) in a pure and ophthalmic formulation. The method depends on complexation of HGAT with Co (II), Ni (II) and La(III) ions in ethanol medium at room temperature. The experimental conditions have been investigated to reach optimum conditions for HGAT-metal ions interaction, including detection of a suitable wavelength, medium pH, reaction time and reactants concentration. Moreover, the composition of these complexes in addition to their stability constants were also investigated and the result indicated that the molar ratio of HGAT: Metal ion is 1:1 for Ni (II) and La(III) ions and 1:2 for Co (II) ion. Beer's law plots were obeyed in the concentration ranges 18.77-150.16, 18.77-131.39 and 18.77-112.62 (μg mL

Indexed as

GatifloxacinHGAT-metal ions interactionOphthalmic formulationSpectrophotometry

Identifiers

PMID33537484
PMCPMC7841363

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.