Evidence map›Paper›PMID 33537299›Full record

ArticleFrontiers in cell and developmental biology2020

A Rapid and Highly Predictive

Li-Tzu Wang, Yu-Wei Lee, Chyi-Huey Bai, Hui-Chun Chiang, Hsiu-Huan Wang, B Linju Yen, Men-Luh Yen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Li-Tzu WangDepartment of Obstetrics and Gynecology, National Taiwan University (NTU) Hospital and College of Medicine, Taipei, Taiwan.
Yu-Wei LeeRegenerative Medicine Research Group, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan.
Chyi-Huey BaiSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Hui-Chun ChiangDepartment of Obstetrics and Gynecology, National Taiwan University (NTU) Hospital and College of Medicine, Taipei, Taiwan.
Hsiu-Huan WangRegenerative Medicine Research Group, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan.
B Linju YenRegenerative Medicine Research Group, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan.
Men-Luh YenDepartment of Obstetrics and Gynecology, National Taiwan University (NTU) Hospital and College of Medicine, Taipei, Taiwan.
National Health Research Institutes · TWNational Taiwan University Hospital · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid aging of worldwide populations had led to epidemic increases in the incidence of osteoporosis (OP), but while treatments are available, high cost, adverse effects, and poor compliance continue to be significant problems. Naturally occurring plant-based compounds including phytoestrogens can be good and safe candidates to treat OP, but screening for osteogenic capacity has been difficult to achieve, largely due to the requirement of using primary osteoblasts or mesenchymal stem cells (MSCs), the progenitors of osteoblasts, to conduct time-consuming

Indexed as

drug screening platformluciferase promoter assaymesenchymal stem cellsosteoporosisRunx2

Identifiers

PMID33537299
PMCPMC7849832
OpenAlexW3120520321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.