Evidence map›Paper›PMID 33537112›Full record

ArticleBiomicrofluidics2021

Bandpass sorting of heterogeneous cells using a single surface acoustic wave transducer pair.

Gergely Simon, Caroline Busch, Marco A B Andrade, Julien Reboud, Jonathan M Cooper, Marc P Y Desmulliez, Mathis O Riehle, Anne L Bernassau

Abstract read
In one paragraph

Article in Biomicrofluidics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gergely SimonSchool of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.ORCID 0000-0003-3483-8947
Caroline BuschInstitute of Molecular Cell and Systems Biology, Centre for Cell Engineering, University of Glasgow, Glasgow G12 8QQ, United Kingdom.ORCID 0000-0001-5608-2218
Marco A B AndradeInstitute of Physics, University of São Paulo, São Paulo 05508-090, Brazil.ORCID 0000-0002-1711-7358
Julien ReboudJames Watt School of Engineering, University of Glasgow, Glasgow G12 8LT, United Kingdom.ORCID 0000-0002-6879-8405
Jonathan M CooperJames Watt School of Engineering, University of Glasgow, Glasgow G12 8LT, United Kingdom.ORCID 0000-0002-2358-1050
Marc P Y DesmulliezSchool of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.ORCID 0000-0002-2441-1598
Mathis O RiehleInstitute of Molecular Cell and Systems Biology, Centre for Cell Engineering, University of Glasgow, Glasgow G12 8QQ, United Kingdom.ORCID 0000-0001-7988-1514
Anne L BernassauSchool of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, United Kingdom.ORCID 0000-0002-0335-546X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Separation and sorting of biological entities (viruses, bacteria, and cells) is a critical step in any microfluidic lab-on-a-chip device. Acoustofluidics platforms have demonstrated their ability to use physical characteristics of cells to perform label-free separation. Bandpass-type sorting methods of medium-sized entities from a mixture have been presented using acoustic techniques; however, they require multiple transducers, lack support for various target populations, can be sensitive to flow variations, or have not been verified for continuous flow sorting of biological cells. To our knowledge, this paper presents the first acoustic bandpass method that overcomes all these limitations and presents an inherently reconfigurable technique with a single transducer pair for stable continuous flow sorting of blood cells. The sorting method is first demonstrated for polystyrene particles of sizes 6, 10, and 14.5

Identifiers

PMID33537112
PMCPMC7843154

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.