Evidence map›Paper›PMID 33537100›Full record

ArticleTheranostics2021

Cell membranes targeted unimolecular prodrug for programmatic photodynamic-chemo therapy.

Jie Yuan, Rong Peng, Dongdong Su, Xingxing Zhang, Hepeng Zhao, Xiujuan Zhuang, Mei Chen, Xiaobing Zhang, Lin Yuan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Hollow CuInternational journal of nanomedicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie YuanState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R China.
Rong PengState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R China.
Dongdong SuDepartment of Chemistry and Chemical Engineering, Beijing University of Technology, Beijing, 100124, P. R. China.
Xingxing ZhangState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R China.
Hepeng ZhaoCollege of Physics and Microelectronics Science, Hunan University, Changsha 410082, P. R China.
Xiujuan ZhuangCollege of Physics and Microelectronics Science, Hunan University, Changsha 410082, P. R China.
Mei ChenCollege of Materials Science and Engineering, Hunan University, Changsha 410082, P. R China.
Xiaobing ZhangState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R China.
Lin YuanState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R China.
Beijing University of Technology · CNHunan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) has emerged as one of the most up-and-coming non-invasive therapeutic modalities for cancer therapy in rencent years. However, its therapeutic effect was still hampered by the short life span, limited diffusion distance and ineluctable depletion of singlet oxygen (

Indexed as

PhotonsAnimalsAzo CompoundsCell MembraneFemaleFluorescent DyesHeLa CellsHumansHypoxiaMammary Neoplasms, ExperimentalPhotochemotherapyPhotosensitizing AgentsProdrugsRhodaminesSinglet OxygenStaining and LabelingAzo CompoundsFluorescent DyesPhotosensitizing AgentsProdrugsRhodaminesSinglet Oxygencell membranecombination therapyglutathionesinglet oxygentwo-photon photodynamic therapy

Identifiers

PMID33537100
PMCPMC7847693
OpenAlexW3126557310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.