Evidence map›Paper›PMID 33537075›Full record

ArticleTheranostics2021

Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.

Bohan Zhang, Hanlin Xu, Jun Chen, Xiaoxia Zhu, Yu Xue, Yifan Yang, Jianpeng Ao, Yinghui Hua, Minbiao Ji

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

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  15. Quantitative Stimulated Raman Scattering Microscopy: Promises and Pitfalls.Annual review of analytical chemistry (Palo Alto, Calif.) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bohan ZhangState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Hanlin XuDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jun ChenDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Xiaoxia ZhuDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yu XueDepartment of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yifan YangState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Jianpeng AoState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Yinghui HuaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Minbiao JiState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan University, Shanghai 200433, China.
Huashan Hospital · CNState Key Laboratory of Surface PhysicsFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gout is a common metabolic disease with growing burden, caused by monosodium urate (MSU) microcrystal deposition. In situ and chemical-specific histological identification of MSU is crucial in the diagnosis and management of gout, yet it remains inaccessible for current histological methods.

Indexed as

AnimalsChinaDisease Models, AnimalGoutHistological TechniquesHumansMaleMiddle AgedRatsRats, Sprague-DawleySpectrum Analysis, RamanSynovial FluidUric AcidUric Acidgoutlabel-free histologymonosodium uratestimulated Raman scattering

Identifiers

PMID33537075
PMCPMC7847673
OpenAlexW3119543580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.