Evidence map›Paper›PMID 33537027›Full record

ArticleFrontiers in immunology2020

Donor-Derived Myeloid Heme Oxygenase-1 Controls the Development of Graft-Versus-Host Disease.

Chloé Spilleboudt, Virginie De Wilde, Philippe Lewalle, Ludovic Cabanne, Mathieu Leclerc, Florence Beckerich, Dominique Bories, Silvia Cardoso, Miguel P Soares, Benoît Vokaer and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Dual roles of CD11bFrontiers in immunology · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Chloé SpilleboudtInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Virginie De WildeInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Philippe LewalleJules Bordet Institute, Hematology Department, Université libre de Bruxelles, Brussels, Belgium.
Ludovic CabanneAP-HP, Hôpital Henri Mondor, Department of Hematology, Créteil, France.
Mathieu LeclercAP-HP, Hôpital Henri Mondor, Department of Hematology, Créteil, France.
Florence BeckerichAP-HP, Hôpital Henri Mondor, Department of Hematology, Créteil, France.
Dominique BoriesAP-HP, Hôpital Henri Mondor, Department of Hematology, Créteil, France.
Silvia CardosoInstituto Gulbenkian de Ciência, Oeiras, Portugal.
Miguel P SoaresInstituto Gulbenkian de Ciência, Oeiras, Portugal.
Benoît VokaerInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Jean-Michel HougardyErasme Hospital, Nephrology and Internal Medicine Department, Université libre de Bruxelles, Brussels, Belgium.
Véronique FlamandInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Judith RacapéErasme Hospital, Nephrology and Internal Medicine Department, Université libre de Bruxelles, Brussels, Belgium.
Marc AbramowiczDepartment of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Sébastien MauryAP-HP, Hôpital Henri Mondor, Department of Hematology, Créteil, France.
Alain Le MoineInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Université Libre de Bruxelles · BEUniversité Paris-Est Créteil · FRAssistance Publique – Hôpitaux de Paris · FRInstituto Gulbenkian de Ciência · PTInstitut Jules Bordet · BEUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graft-versus-host disease (GVHD) remains a major clinical drawback of allogeneic hematopoietic stem cell transplantation (HSCT). Here, we investigated how the stress responsive heme catabolizing enzyme heme oxygenase-1 (HO-1, encoded by

Indexed as

AdultAnimalsDisease Models, AnimalFemaleGenetic Predisposition to DiseaseGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHeme Oxygenase-1HomozygoteHumansMaleMembrane ProteinsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutHeme Oxygenase-1HMOX1 protein, humanHmox1 protein, mouseMembrane Proteinsgraft-versus-host diseasehematopoeietic stem cell transplantationHeme oxygenase-1myeloid-derived suppressor cellspolymorphismtransplantation

Identifiers

PMID33537027
PMCPMC7849683
OpenAlexW3125594975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.