Evidence map›Paper›PMID 33536914›Full record

ArticleFrontiers in pharmacology2020

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Ascending Dose and Food Effect Study to Evaluate the Tolerance, Pharmacokinetics of Jaktinib, a New Selective Janus Kinase Inhibitor in Healthy Chinese Volunteers.

Jingrui Liu, Binhua Lv, Hewen Yin, Xiaoxue Zhu, Haijing Wei, Yanhua Ding

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07185633 (A Prospective, Single-Arm, Phase II Clinical Study of Gecacitinib-Corticosteroids as First-Line Treatment for Grade II-IV Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07185633 phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Single-Arm, Phase II Clinical Study of Gecacitinib-Corticosteroids as First-Line Treatment for Grade II-IV Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

TypeinterventionalSponsorBin GuRan2025 to 2027Enrolled25ConditionsaGVHDArmsGecacitinib-Corticosteroid, Methylprednisolone sodium succinate
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  12. Challenges and Future Trends in Atopic Dermatitis.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingrui LiuPhase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.
Binhua LvSuzhou Zelgen Biopharmaceuticals Co., Ltd., Jiangsu, China.
Hewen YinSuzhou Zelgen Biopharmaceuticals Co., Ltd., Jiangsu, China.
Xiaoxue ZhuPhase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.
Haijing WeiPhase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.
Yanhua DingPhase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

food effectjaktinibpharmacokineticsphase Isafety

Identifiers

PMID33536914
PMCPMC7849180

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.