Evidence map›Paper›PMID 33536855›Full record

ArticleJournal of interventional cardiology2021

Comparison of Mortality Risk Models in Patients with Postcardiac Arrest Cardiogenic Shock and Percutaneous Mechanical Circulatory Support.

Georgios Chatzis, Birgit Markus, Styliani Syntila, Christian Waechter, Ulrich Luesebrink, Holger Ahrens, Dimitar Divchev, Bernhard Schieffer, Konstantinos Karatolios

Open access · goldAbstract read
In one paragraph

Article in Journal of interventional cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Georgios ChatzisDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0003-2258-0846
Birgit MarkusDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-0485-5722
Styliani SyntilaDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0001-5784-5563
Christian WaechterDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0003-1558-0696
Ulrich LuesebrinkDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-7588-1602
Holger AhrensDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-3954-9864
Dimitar DivchevDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0002-3062-3271
Bernhard SchiefferDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0003-0660-6102
Konstantinos KaratoliosDepartment of Cardiology, Angiology and Intensive Care, Philipps University Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0001-7996-7019
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough scoring systems are widely used to predict outcomes in postcardiac arrest cardiogenic shock (CS) after out-of-hospital cardiac arrest (OHCA) complicating acute myocardial infarction (AMI), data concerning the accuracy of these scores to predict mortality of patients treated with Impella in this setting are lacking. Thus, we aimed to evaluate as well as to compare the prognostic accuracy of acute physiology and chronic health II (APACHE II), simplified acute physiology score II (SAPS II), sepsis-related organ failure assessment (SOFA), the intra-aortic balloon pump (IABP), CardShock, the prediction of cardiogenic shock outcome for AMI patients salvaged by VA-ECMO (ENCOURAGE), and the survival after venoarterial extracorporeal membrane oxygenation (SAVE) score in patients with OHCA refractory CS due to an AMI treated with Impella 2.5 or CP.

methodsRetrospective study of 65 consecutive Impella 2.5 and 32 CP patients treated in our cardiac arrest center from September 2015 until June 2020.

resultsOverall survival to discharge was 44.3%. The expected mortality according to scores was SOFA 70%, SAPS II 90%, IABP shock 55%, CardShock 80%, APACHE II 85%, ENCOURAGE 50%, and SAVE score 70% in the 2.5 group; SOFA 70%, SAPS II 85%, IABP shock 55%, CardShock 80%, APACHE II 85%, ENCOURAGE 75%, and SAVE score 70% in the CP group. The ENCOURAGE score was the most effective predictive model of mortality outcome presenting a moderate area under the curve (AUC) of 0.79, followed by the CardShock, APACHE II, IABP, and SAPS score. These derived an AUC between 0.71 and 0.78. The SOFA and the SAVE scores failed to predict the outcome in this particular setting of refractory CS after OHCA due to an AMI.

conclusionThe available intensive care and newly developed CS scores offered only a moderate prognostic accuracy for outcomes in OHCA patients with refractory CS due to an AMI treated with Impella. A new score is needed in order to guide the therapy in these patients.

Indexed as

Extracorporeal Membrane OxygenationOut-of-Hospital Cardiac ArrestShock, CardiogenicAgedCritical CareFemaleHumansIntra-Aortic Balloon PumpingMaleMiddle AgedOrgan Dysfunction ScoresPrognosisRetrospective StudiesRisk AssessmentSurvival Analysis

Identifiers

PMID33536855
PMCPMC7834787
OpenAlexW3125961108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.