Evidence map›Paper›PMID 33536714›Full record

ArticleJournal of clinical biochemistry and nutrition2021

Effects of French maritime pine bark/bilberry fruit extracts on intraocular pressure for primary open-angle glaucoma.

Kaoru Manabe, Sachiko Kaidzu, Aika Tsutsui, Mihoko Mochiji, Yotaro Matsuoka, Yasutaka Takagi, Etsuyo Miyamoto, Masaki Tanito

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kaoru ManabeDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya, Izumo, Shimane 693-8501 Japan.
Sachiko KaidzuDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya, Izumo, Shimane 693-8501 Japan.
Aika TsutsuiDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya, Izumo, Shimane 693-8501 Japan.
Mihoko MochijiDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya, Izumo, Shimane 693-8501 Japan.
Yotaro MatsuokaDivision of Ophthalmology, Matsue Red Cross Hospital, Matsue, Shimane 690-8506, Japan.
Yasutaka TakagiSanten Pharmaceutical Co. Ltd., Osaka 530-8552, Japan.
Etsuyo MiyamotoSanten Pharmaceutical Co. Ltd., Osaka 530-8552, Japan.
Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya, Izumo, Shimane 693-8501 Japan.
Shimane University · JPMatsue Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested oral French maritime pine bark (40 mg)/bilberry fruit extract (90 mg) supplements for intraocular pressure-lowering effects in Japanese subjects with primary open-angle glaucoma. Eighteen subjects (29 eyes) were recruited with intraocular pressure of ≥15 mmHg who used one to three bottles of antiglaucoma medications. After a 2-week observation (period 1), subjects ingested a tablet/day of Sante

Indexed as

anthocyaninbiological antioxidant potential (BAP) testdiacron reactive oxygen metabolites (dROM) testMirtoselect®procyanidinPycnogenol®sulfhydryl (SH) test

Identifiers

PMID33536714
PMCPMC7844666
OpenAlexW3040848047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.