Evidence map›Paper›PMID 33536214›Full record

ArticleScience advances2021

A single-nucleotide change underlies the genetic assimilation of a plastic trait.

Paul Vigne, Clotilde Gimond, Céline Ferrari, Anne Vielle, Johan Hallin, Ania Pino-Querido, Sonia El Mouridi, Laure Mignerot, Christian Frøkjær-Jensen, Thomas Boulin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  4. Description ofJournal of nematology · 2026
    Article
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  6. Molecular mechanisms underlying the evolution of a color polyphenism by genetic accommodation in the tobacco hornworm,Proceedings of the National Academy of Sciences of the United States of America · 2025
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  15. A theoretical perspective on Waddington's genetic assimilation experiments.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Paul VigneUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.ORCID 0000-0002-7927-7920
Clotilde GimondUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.ORCID 0000-0003-1708-4629
Céline FerrariUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.
Anne VielleUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.
Johan HallinUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.ORCID 0000-0003-0586-9576
Ania Pino-QueridoIBENS, Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University, F-75005 Paris, France.ORCID 0000-0001-6830-4148
Sonia El MouridiInstitut NeuroMyoGène, CNRS, Inserm, Université de Lyon, Lyon, France.
Laure MignerotUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France.ORCID 0000-0003-3306-6244
Christian Frøkjær-JensenKing Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0002-3178-0906
Thomas BoulinInstitut NeuroMyoGène, CNRS, Inserm, Université de Lyon, Lyon, France.ORCID 0000-0002-1734-1915
Henrique TeotónioIBENS, Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University, F-75005 Paris, France.ORCID 0000-0003-1057-6882
Christian BraendleUniversité Côte d'Azur, CNRS, Inserm, IBV, Nice, France. braendle@unice.fr.
Centre National de la Recherche Scientifique · FRUniversité Claude Bernard Lyon 1 · FRKing Abdullah University of Science and Technology · SA

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Genetic assimilation-the evolutionary process by which an environmentally induced phenotype is made constitutive-represents a fundamental concept in evolutionary biology. Thought to reflect adaptive phenotypic plasticity, matricidal hatching in nematodes is triggered by maternal nutrient deprivation to allow for protection or resource provisioning of offspring. Here, we report natural

Identifiers

PMID33536214
PMCPMC7857674
OpenAlexW3128179043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.