Evidence map›Paper›PMID 33536174›Full record

ArticleJournal of virology2021

Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.

Jingjing Liang, Gordon Ruthel, Cari A Sagum, Mark T Bedford, Sachdev S Sidhu, Marius Sudol, Chaitanya K Jaladanki, Hao Fan, Bruce D Freedman, Ronald N Harty

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Role of angiomotin family members in human diseases (Review).Experimental and therapeutic medicine · 2024
    Review
  5. Chaperone-assisted selective autophagy targets filovirus VP40 as a client and restricts egress of virus particles.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Jingjing LiangDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA, USA.
Gordon RuthelDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA, USA.
Cari A SagumDepartment of Epigenetics & Molecular Carcinogenesis, M.D. Anderson Cancer Center, University of Texas, Smithville, Texas, USA.
Mark T BedfordDepartment of Epigenetics & Molecular Carcinogenesis, M.D. Anderson Cancer Center, University of Texas, Smithville, Texas, USA.
Sachdev S SidhuDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Marius SudolDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Chaitanya K JaladankiBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore 138671.
Hao FanBioinformatics Institute, Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore 138671.
Bruce D FreedmanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA, USA.
Ronald N HartyDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA, USA rharty@vet.upenn.edu.ORCID https://orcid.org/0000-0001-6596-0414
University of Pennsylvania · USAgency for Science, Technology and Research · SGThe University of Texas MD Anderson Cancer Center · USIcahn School of Medicine at Mount Sinai · USUniversity of Toronto · CA

Funding

Dueling PPxY Motifs of Filovirus VP40 and Host Angiomotin: Effects on Innate Immune Defenses and Tight Junction Integrity at Immune Privileged SitesR21AI139392 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2018 to 2019
$462k
Modular Domains of Host Proteins Regulate Filovirus MaturationR21AI138052 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2018 to 2019
$448k
Predicted Role of Ebola VP40-Host Interactions in Ocular Pathology and PersistenceR21EY031465 · NEI · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2020 to 2021
$440k
NEI NIH HHS R21 EY031465NIAID NIH HHS R21 AI138052NIAID NIH HHS R21 AI139392
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33536174
PMCPMC8103691
OpenAlexW3128975004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.