Evidence map›Paper›PMID 33536127›Full record

ArticleGynecologic oncology2021

Assessment of physical function by subjective and objective methods in patients undergoing open gynecologic surgery.

Xin Shelley Wang, Mona Kamal, Tsun Hsuan Chen, Qiuling Shi, Araceli Garcia-Gonzalez, Maria D Iniesta, Charles S Cleeland, Vijaya Gottumukkala, Larissa A Meyer

Abstract read
In one paragraph

Article in Gynecologic oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. From questionnaires to single items: independent use of a walking measure in patients after thoracic surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Patient-reported symptoms at discharge and risk of complications after gynecologic surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin Shelley WangDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America. Electronic address: xswang@mdanderson.org.
Mona KamalDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Tsun Hsuan ChenDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Qiuling ShiDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Araceli Garcia-GonzalezDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Maria D IniestaDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Charles S CleelandDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Vijaya GottumukkalaDepartment of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Larissa A MeyerDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Improving Recovery after Major Cancer Surgery using Patient-Reported OutcomesR01CA205146 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WANG, XIN SHELLEY · 2016 to 2019
$2.6M
Health Services Career Development: Improving Medical Decisions in Ovarian CancerK07CA201013 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MEYER, LARISSA ALEJANDRA · 2016 to 2020
$853k
NCI NIH HHS K07 CA201013NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA205146
6 · The paper itself

Abstract

objectiveTo evaluate the utility of patient-reported outcomes (PROs) to measure physical functioning in perioperative care for patients with gynecological (GYN) tumors.

methods180 patients with GYN tumors undergoing open surgery participated in this longitudinal study. The physical functioning was measured by a subjective PRO tool, the Interference subscales of the MD Anderson Symptom Inventory (MDASI-I); as well as by an objective tool, the Timed Up & Go test (TUGT), perioperatively. Longer time (>20 s) needed to complete the TUGT was defined as "Prolonged". Patients completed EuroQoL-5D as well. The association between the scores of MDASI-I items and TUGT was assessed via the Spearman correlation coefficient. The known-group validity was assessed using the t-test and Cohen's D effect size.

resultsCompliance rates at preoperative, discharge and postoperative time points of MDASI-I were 98%, 95%, 96%; while TUGT completion rates were 92%, 75%, and 80%, respectively. Patients who had refused TUGT at discharge reported a significantly worse "MDASI-general activity" score compared to patients who completed TUGT (mean score of 7.00 vs. 5.38, P = 0.020). Patient-reported "Walking" on MDASI-I significantly differentiated patients with prolonged vs. those with frail/normal TUGT at discharge (mean score of 4.89 vs. 2.79, Cohen's d effect size = 0.82, P < 0.001). MDASI-I demonstrated excellent known-group validity per performance status and for the EuroQoL-5D subscales.

conclusionPatient-reported physical functioning impairment after GYN surgery correspond with observed worse scores of the objective functioning measure test (TUGT). MDASI-I assessment represents a feasible and valid tool to evaluate functional status and warrants further implementation in the perioperative setting.

Indexed as

FemaleGenital Neoplasms, FemaleGynecologic Surgical ProceduresHumansLongitudinal StudiesMiddle AgedPatient Reported Outcome MeasuresPerioperative PeriodPostoperative PeriodSeverity of Illness IndexSymptom AssessmentFunctioning measureGet up & go test (TUGT)GynecologicalMDASIPRO

Identifiers

PMID33536127
PMCPMC7994186

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.