ArticleEpidemiology and psychiatric sciences2021
Excess mortality in patients with schizophrenia spectrum disorders in Malaga (Spain): A cohort study.
Article in Epidemiology and psychiatric sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cannabis use and suicide in people with a diagnosis of schizophrenia: a systematic review and meta-analysis of longitudinal, case control, and cross-sectional studies.Psychological medicine · 2025Pooled it
- The Role of Socioeconomic Position in the Association Between Mental Disorders and Mortality: A Systematic Review and Meta-Analysis.JAMA psychiatry · 2024Pooled it
- Does life expectancy vary by disability status in LMICs?: A systematic review and meta-analysis.African journal of disability · 2025Review
- Associations between suicide attempts and clinical, metabolic, and inflammatory markers in Chinese patients with long-term schizophrenia.Frontiers in psychiatry · 2025Article
- Integrating Electronic Health Records and Polygenic Risk to Identify Genetically Unrelated Comorbidities of Schizophrenia That May Be Modifiable.Biological psychiatry global open science · 2024Article
- Mentalization-based approach for schizophrenia spectrum disorders: a psychotherapeutic proposal for evolved schizophrenic trajectories and serious mental disorders.Frontiers in psychiatry · 2024Article
- Life expectancy and years of potential life lost in people with mental disorders: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Excess mortality in a cohort of Brazilian patients with a median follow-up of 11 years after the first psychiatric hospital admission.Social psychiatry and psychiatric epidemiology · 2023Article
- Breast Cancer Care Pathways for Women with Preexisting Severe Mental Disorders: Evidence of Disparities in France?Journal of clinical medicine · 2023Article
- Pre-existing chronic physical morbidity and excess mortality in people with schizophrenia: a population-based cohort study.Social psychiatry and psychiatric epidemiology · 2022Article
- Schizophrenia and Hospital Admissions for Cardiovascular Events in a Large Population: The APNA Study.Journal of cardiovascular development and disease · 2022Article
- Mortality and excess life-years lost in patients with schizophrenia under community care: a 5-year follow-up cohort study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThere is evidence that patients with schizophrenia spectrum disorders present higher mortality in comparison with the general population. The aim of this study was to analyse the causes of mortality and sociodemographic factors associated with mortality, standardised mortality ratios (SMRs), life expectancy and potential years of life lost (YLL) in patients with schizophrenia spectrum disorders in Spain.
methodsThe study included a cohort of patients from the Malaga Schizophrenia Case Register (1418 patients; 907 males; average age 42.31 years) who were followed up for a minimum of 10 years (median = 13.43). The factors associated with mortality were analysed with a survival analysis using Cox's proportional hazards regression model.
resultsThe main causes of mortality in the cohort were circulatory disease (21.45%), cancer (17.09%) and suicide (13.09%). The SMR of the cohort was more than threefold that of the population of Malaga (3.19). The life expectancy at birth was 67.11 years old, which is more than 13 years shorter than that of the population of Malaga. The YLL was 20.74. The variables associated with a higher risk of mortality were age [adjusted hazard ratio (AHR) = 1.069, p < 0.001], male gender (AHR = 1.751, p < 0.001) and type of area of residence (p = 0.028; deprived urban zone v. non-deprived urban area, AHR = 1.460, p = 0.028). In addition, receiving welfare benefit status in comparison with employed status (AHR = 1.940, p = 0.008) was associated with increased mortality.
conclusionsThere is excess mortality in patients with schizophrenia spectrum disorders and also an association with age, gender, socioeconomic inequalities and receiving welfare benefits. Efforts directed towards improved living conditions could have a positive effect on reducing mortality.
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