Evidence map›Paper›PMID 33536098›Full record

SynthesisParasitology2021

A systematic review of anti-

Saeed Nezaratizade, Nooshin Hashemi, Davood Ommi, Ilkay Erdogan Orhan, Faham Khamesipour

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Induction of apoptosis by hydroalcoholic and methanolic extract ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  4. Anti-Interdisciplinary perspectives on infectious diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Saeed NezaratizadeYoung Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.ORCID 0000-0001-9600-4767
Nooshin HashemiSchool of Medicine, Bam University of Medical Sciences, Bam, Iran.ORCID 0000-0002-0933-8134
Davood OmmiFunctional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3225-7535
Ilkay Erdogan OrhanDepartment of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey.ORCID 0000-0002-7379-5436
Faham KhamesipourShahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-0678-2528
Shahid Beheshti University of Medical Sciences · IRBam University of Medical Sciences · IRGazi University · TRIslamic Azad University of Shahrekord · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amoebiasis has emerged as a major health problem worldwide. It is endemic in the present scenario is different and sub-tropical regions especially in Asia, Latin America and also in Africa. Causative of amoebiasis is a protozoan known as Entamoeba histolytica. We screened all the databases such as PubMed, Science Direct, Medline and Google Scholar by using the keywords ‘anti-Entamoeba histolytica activity of medicinal plants, anti-Entamoeba histolytica activity of herbal drugs, the anti-amoebic activity of natural drugs’. In the present study, we found 7861 articles, where all articles were screened for bias analysis and included 32 full-matching articles in total reporting the use of medicinal plants as a remedy for amoebiasis. Through these articles, we found 42 herbs having anti-amoebic activity. In bias analysis, we also found four articles under high bias risk. In our study, seven medicinal plants were concluded to possess the most potent anti-amoebic activity based on their IC50 value, which was less than 1 μg mL−1. On bias analysis, we found four articles with high bias risk, hence these studies can be repeated for better results.

Indexed as

Antiprotozoal AgentsEntamoeba histolyticaInhibitory Concentration 50Plant PreparationsPlants, MedicinalAntiprotozoal AgentsPlant PreparationsAnti-amoebic activityanti-Entamoeba histolytica activitymedicinal plantsPRISMA

Identifiers

PMID33536098
PMCPMC11010214
OpenAlexW3126537088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.