ArticleBMC public health2021
A qualitative meta-synthesis of facilitators and barriers to tuberculosis diagnosis and treatment in Nigeria.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Community-based interventions to improve tuberculosis treatment outcomes: A meta-analysis.MethodsX · 2026Review
- Barriers to the diagnosis and treatment of tuberculosis in Abidjan, Côte d'Ivoire: a qualitative study.BMC public health · 2026Article
- Multidrug-resistant tuberculosis (MDR-TB): an evolving threat to the Nigerian health system - a review.Annals of medicine and surgery (2012) · 2026Review
- Article
- Social isolation, social exclusion, and access to mental and tangible resources: mapping the gendered impact of tuberculosis-related stigma among men and women living with tuberculosis in Eastern Cape Province, South Africa.BMC global and public health · 2025Article
- Uncertainty in tuberculosis clinical decision-making: An umbrella review with systematic methods and thematic analysis.PLOS global public health · 2024Article
- The TB Surge intervention: an optimized approach to TB case-finding in Nigeria.Public health action · 2023Article
- Tuberculous meningitis patient pathways and delays to diagnosis in Indonesia: a retrospective cohort study.BMJ public health · 2023Article
- Building bridges: multidisciplinary teams in tuberculosis prevention and care.Breathe (Sheffield, England) · 2023Article
- Bibliometric structured review of tuberculosis in Nigeria.African health sciences · 2023Article
- Barriers to childhood tuberculosis case detection and management in Cambodia: the perspectives of healthcare providers and caregivers.BMC infectious diseases · 2023Article
- Total delay and associated factors among tuberculosis patients in Jimma Zone, Southwest Ethiopia.PloS one · 2023Article
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite progress in tuberculosis (TB) control globally, TB continues to be a leading cause of death from infectious diseases, claiming 1.2 million lives in 2018; 214,000 of these deaths were due to drug resistant strains. Of the estimated 10 million cases globally in 2018, 24% were in Africa, with Nigeria and South Africa making up most of these numbers. Nigeria ranks 6th in the world for TB burden, with an estimated 4.3% multi-drug resistance in new cases. However, the country had one of the lowest case detection rates, estimated at 24% of incident cases in 2018 - well below the WHO STOP TB target of 84%. This rate highlights the need to understand contextual issues influencing tuberculosis management in Nigeria. Our synthesis was aimed at synthesizing qualitative evidence on factors influencing TB care in Nigeria.
methodsA three-stage thematic meta-synthesis of qualitative studies was used to identify barriers and facilitators to tuberculosis case finding and treatment in Nigeria. A search of eleven databases was conducted. The date of publication was limited to 2006 to June 2020. We analyzed articles using a three-stage process, resulting in coding, descriptive subthemes and analytical themes.
resultsOur final synthesis of 10 articles resulted in several categories including community and family involvement, education and knowledge, attitudes and stigma, alternative care options, health system factors (including coverage and human resource), gender, and direct and indirect cost of care. These were grouped into three major themes: individual factors; interpersonal influences; and health system factors.
conclusionCase finding and treatment for TB in Nigeria currently depends more on individual patients presenting voluntarily to the hospital for care, necessitating an understanding of patient behaviors towards TB diagnosis and treatment. Our synthesis has identified several related factors that shape patients' behavior towards TB management at individual, community and health system levels that can inform future interventions.
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