Evidence map›Paper›PMID 33535974›Full record

ArticleBMC infectious diseases2021

Tuberculosis (TB) in the refugee camps in Ethiopia: trends of case notification, profile, and treatment outcomes, 2014 to 2017.

Tsegay Legesse, Goitom Admenur, Selemawit Gebregzabher, Eyob Woldegebriel, Bexabeh Fantahun, Yemane Tsegay, Abeyot Bayssa, Berihu Darge, Yidnekachew Denbu, Hayelom Michalel and 4 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Prevalence ofIJID regions · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prevalence of Smear-Positive, Rifampicin-ResistantInfection and drug resistance · 2024
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tsegay LegesseInter-Governmental Authority on Development (IGAD), Djibouti, Djibouti.
Goitom AdmenurAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Selemawit GebregzabherAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Eyob WoldegebrielAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Bexabeh FantahunAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Yemane TsegayAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Abeyot BayssaAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Berihu DargeAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Yidnekachew DenbuAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Hayelom MichalelAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Kibebew AberaAdministration for Refugee and Returnee Affairs, Addis Ababa, Ethiopia.
Abraham AlemayehFederal Ministry of Health, Addis Ababa, Ethiopia.
Dejene KebedeUnited Nations Higher Commision for Refugees, Addis Ababa, Ethiopia.
Desta KasaInter-Governmental Authority on Development (IGAD), Djibouti, Djibouti. dkassa2003@gmail.com.ORCID http://orcid.org/0000-0003-0624-8122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeverity of TB increases in refugee populations. Monitoring TB case notification and treatment outcomes are essential to improve the effectiveness of TB programs. This study aimed to investigate trends in TB case notification and treatment outcomes and explore factors associated with unsuccessful treatment outcome in refugee camps in Ethiopia.

methodsIn this retrospective cohort study, demographic and clinical data of all TB cases registered in 25 refugee camps in Ethiopia from January 2014 to December 2017 were extracted. Multivariate logistic regression was fitted to estimate odds ratios and corresponding 95% confidence intervals for the measure of association linked with factors significantly associated with unsuccessful treatment outcomes.

resultsA total of 1553 TB cases, mean age 27.7 years, were registered from 2014 to 2017. Of these notified cases 54.7% were men, 27.7% children (< 15 years), 71.2% pulmonary TB (PTB), 27.8% Extra-PTB (EPTB) and 98.3% new and relapse. From 2014 to 2017: there was consistent increase in number of notified TB cases (138 to 588 cases), in percentage of EPTB (23.2 to 32.7%), in contribution of children to total TB cases (18.8 to 30.1%) and to EPTB (40.6 to 65.1%), and in proportion of bacteriologically confirmed new and relapse pulmonary cases (43.8 to 64.8%). Treatment success rates for all TB cases remained lower at 72.7-79.4%. On average 24.8% had unfavorable treatment outcome, including 11.5% not evaluated, 8.0% LTFU, 4.8% died and 0.5% treatment failed. Unsuccessful treatment was significantly associated with pretreatment weight below 40 Kg, age over 45 years, and being HIV positive.

conclusionsThere was continuous increase in notified TB cases and in percentage of childhood TB. Proportion of bacteriologically confirmed new and relapse pulmonary cases increased overtime. TB treatment success remained lower than the national achievement in 2017 (96%) and global target (> = 90%), which needs improvement. The higher LTFU, not evaluated, and death suggests the need to strengthen adherence education and supervision. Special socio-economic support and monitoring is required for patients with pretreatment weight below 40 Kg, age over 45 years and HIV positives.

Indexed as

Disease NotificationTreatment OutcomeAdolescentAdultChildEthiopiaFemaleHumansMaleMiddle AgedRefugee CampsRefugeesRetrospective StudiesTuberculosisYoung AdultCase notificationRefugee campsRefugeesTreatment outcomeTuberculosis

Identifiers

PMID33535974
PMCPMC7856765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.