ArticleBMC genomics2021
Authoritative subspecies diagnosis tool for European honey bees based on ancestry informative SNPs.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Multiple mitogenomes indicate Things Fall Apart with Out of Africa or Asia hypotheses for the phylogeographic evolution of Honey Bees (Apis mellifera).Scientific reports · 2023Pooled it
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- Conservation of Honeybee (Apis mellifera) Intraspecific Diversity Through Reproductive Science and Technology.Advances in experimental medicine and biology · 2026Review
- An XGBoost-Based Morphometric Classification System for Automatic Subspecies Identification ofInsects · 2025Article
- Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspeciesiScience · 2025Article
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- Comparing Morphometric and Mitochondrial DNA Data from Honeybees and Honey Samples for IdentifyingAnimals : an open access journal from MDPI · 2025Article
- COI Metabarcoding as a Novel Approach for Assessing the Honey Bee Source of European Honey.Foods (Basel, Switzerland) · 2025Article
- Accurate Detection ofEcology and evolution · 2024Article
- Genomic diversity and population structure of Carniolan honey bee in its native habitat.BMC genomics · 2024Article
- HBeeID: a molecular tool that identifies honey bee subspecies from different geographic populations.BMC bioinformatics · 2024Article
- Allele Frequencies of Genetic Variants Associated with Varroa Drone Brood Resistance (DBR) inInsects · 2024Article
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- Creation of a Biobank of the Sperm of the Honey Bee Drones of Different Subspecies ofAnimals : an open access journal from MDPI · 2023Article
- Haplotypes of theAnimals : an open access journal from MDPI · 2023Article
- AmelHap: Leveraging drone whole-genome sequence data to create a honey bee HapMap.Scientific data · 2023Article
- Honey bee (Apis mellifera) wing images: a tool for identification and conservation.GigaScience · 2023Article
- Identification of runs of homozygosity in Western honey bees (Ecology and evolution · 2023Article
- Article
Corrections and comments
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Authors and funding
46 authors at 20 institutions in 21 countries.
Funding
Abstract
backgroundWith numerous endemic subspecies representing four of its five evolutionary lineages, Europe holds a large fraction of Apis mellifera genetic diversity. This diversity and the natural distribution range have been altered by anthropogenic factors. The conservation of this natural heritage relies on the availability of accurate tools for subspecies diagnosis. Based on pool-sequence data from 2145 worker bees representing 22 populations sampled across Europe, we employed two highly discriminative approaches (PCA and F
resultsUsing a supervised machine learning (ML) approach and a set of 3896 genotyped individuals, we could show that the 4094 selected single nucleotide polymorphisms (SNPs) provide an accurate prediction of ancestry inference in European honey bees. The best ML model was Linear Support Vector Classifier (Linear SVC) which correctly assigned most individuals to one of the 14 subspecies or different genetic origins with a mean accuracy of 96.2% ± 0.8 SD. A total of 3.8% of test individuals were misclassified, most probably due to limited differentiation between the subspecies caused by close geographical proximity, or human interference of genetic integrity of reference subspecies, or a combination thereof.
conclusionsThe diagnostic tool presented here will contribute to a sustainable conservation and support breeding activities in order to preserve the genetic heritage of European honey bees.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.